[HTML][HTML] The emerging potential for network analysis to inform precision cancer medicine

K Ozturk, M Dow, DE Carlin, R Bejar… - Journal of molecular …, 2018 - Elsevier
Precision cancer medicine promises to tailor clinical decisions to patients using genomic
information. Indeed, successes of drugs targeting genetic alterations in tumors, such as …

Deep learning–based multi-omics integration robustly predicts survival in liver cancer

K Chaudhary, OB Poirion, L Lu, LX Garmire - Clinical Cancer Research, 2018 - AACR
Identifying robust survival subgroups of hepatocellular carcinoma (HCC) will significantly
improve patient care. Currently, endeavor of integrating multi-omics data to explicitly predict …

Deep learning with multimodal representation for pancancer prognosis prediction

A Cheerla, O Gevaert - Bioinformatics, 2019 - academic.oup.com
Motivation Estimating the future course of patients with cancer lesions is invaluable to
physicians; however, current clinical methods fail to effectively use the vast amount of …

The application of bayesian methods in cancer prognosis and prediction

J Chu, NA Sun, W Hu, X Chen, N Yi… - Cancer Genomics & …, 2022 - cgp.iiarjournals.org
With the development of high-throughput biological techniques, high-dimensional omics
data have emerged. These molecular data provide a solid foundation for precision medicine …

[HTML][HTML] A novel risk score model based on eight genes and a nomogram for predicting overall survival of patients with osteosarcoma

G Wu, M Zhang - BMC cancer, 2020 - Springer
Background This study aims to identify a predictive model to predict survival outcomes of
osteosarcoma (OS) patients. Methods A RNA sequencing dataset (the training set) and a …

BSense: A parallel Bayesian hyperparameter optimized Stacked ensemble model for breast cancer survival prediction

P Kaur, A Singh, I Chana - Journal of Computational Science, 2022 - Elsevier
Breast Cancer is a disease with high risk and mortality rate associated with female health.
The multi-omics data having genome, proteome, transcriptome, metabolome data, and …

BhGLM: Bayesian hierarchical GLMs and survival models, with applications to genomics and epidemiology

N Yi, Z Tang, X Zhang, B Guo - Bioinformatics, 2019 - academic.oup.com
BhGLM is a freely available R package that implements Bayesian hierarchical modeling for
high-dimensional clinical and genomic data. It consists of functions for setting up various …

[HTML][HTML] A potential prognostic prediction model of colon adenocarcinoma with recurrence based on prognostic lncRNA signatures

L Jin, C Li, T Liu, L Wang - Human genomics, 2020 - Springer
Background Colon adenocarcinoma (COAD) is one of the common gastrointestinal
malignant diseases, with high mortality rate and poor prognosis due to delayed diagnosis …

Deep learning-based model for predicting progression in patients with head and neck squamous cell carcinoma

Z Zhao, Y Li, Y Wu, R Chen - Cancer Biomarkers, 2020 - content.iospress.com
PURPOSE: This study endeavors to build a deep learning (DL)-based model for predicting
disease progression in head and neck squamous cell carcinoma (HNSCC) patients by …

Tightly integrated genomic and epigenomic data mining using tensor decomposition

J Fang - Bioinformatics, 2019 - academic.oup.com
Motivation Complex diseases such as cancers often involve multiple types of genomic
and/or epigenomic abnormalities. Rapid accumulation of multiple types of omics data …