Recent scientific studies have advanced the notion of chronic inflammation as a major risk
factor underlying aging and age-related diseases. In this review, low-grade, unresolved …

Objective This systematic review aimed to summarize published papers on the effect of
physical activity (PA)/exercise on key atherosclerotic factors in patients with risk factors for or …

Changing lifestyles and an excess of food supply in developed countries have resulted in an
increasing prevalence of overweight and obesity. As a consequence, a disorder of complex …

Atherosclerosis is a chronic immune-inflammatory disease in which the interactions of
monocytes with activated endothelium are crucial events leading to atherosclerotic alteration …

The Influence of Exercise Training on Inflammatory Cytokines and C-Reactive Protein Page 1
Copyright @ 200 by the American College of Sports Medicine. Unauthorized reproduction of …

Two key features of atherosclerotic plaques that precipitate acute atherothrombotic vascular
occlusion (" vulnerable plaques") are abundant inflammatory mediators and macrophages …

Macrophages are central to the initiation and progression of atherosclerosis and thus can be
very appropriate targets for therapy. Cell adhesion molecules mediating monocytes …

Caspase-3 cleavage and activation are known to play central roles in apoptosis. However,
the mechanisms that regulate caspase-3 cleavage remain elusive. Glutaredoxin (Grx) is a …

Increasing evidence demonstrates that interleukin (IL)–32 is a pro-inflammatory cytokine,
inducing IL-1α, IL-1β, IL-6, tumor necrosis factor (TNF)–α, and chemokines via nuclear factor …

Coxibs, such as rofecoxib, celecoxib, and valdecoxib, selectively inhibit cyclooxygenase
(COX)-2, the mainly inducible, pro-inflammatory COX isoform. Unlike traditional non …