Activating mutations in the epidermal growth factor receptor gene occur as early cancer-
driving clonal events in a subset of patients with non-small cell lung cancer (NSCLC) and …

Lung carcinoma is one of the most common human cancers and is estimated to have an
incidence of approximately 2 million new cases per year worldwide with a 20% mortality …

Purpose: Current clinical classification of pancreatic ductal adenocarcinoma (PDAC) is
unable to predict prognosis or response to chemo-or immunotherapy and does not take into …

Adenosquamous carcinoma of the lung (ASC), a relatively rare subtype of non-small-cell
lung cancer, is defined as a malignancy containing components of lung adenocarcinoma …

Adenosquamous lung tumours, which are extremely poor prognosis, may result from cellular
plasticity. Here, we demonstrate lineage switching of KRAS+ lung adenocarcinomas (ADC) …

Human lung adenosquamous cell carcinoma (LUAS), containing both adenomatous and
squamous pathologies, harbors strong plasticity and is significantly associated with poor …

Background Adenosquamous carcinoma (ASC) of the lung is a heterogeneous disease that
is composed of both adenocarcinoma components (ACC) and squamous cell carcinoma …

Background Gallbladder cancer is the most common malignant cancer of the bile ducts and
third most common gastrointestinal malignant in the world for public health. Its relatively low …

Objective Histologic transformation from adenocarcinoma to small cell lung cancer (SCLC)
is one of the mechanisms of acquired resistance after epidermal growth factor receptor …

This overview of the molecular pathology of lung cancer includes a review of the most
salient molecular alterations of the genome, transcriptome, and the epigenome. The insights …