Type 2 diabetes

E Ahmad, S Lim, R Lamptey, DR Webb, MJ Davies - The Lancet, 2022 - thelancet.com
Type 2 diabetes accounts for nearly 90% of the approximately 537 million cases of diabetes
worldwide. The number affected is increasing rapidly with alarming trends in children and …

[HTML][HTML] Nutrition, longevity and disease: From molecular mechanisms to interventions

VD Longo, RM Anderson - Cell, 2022 - cell.com
Diet as a whole, encompassing food composition, calorie intake, and the length and
frequency of fasting periods, affects the time span in which health and functional capacity …

When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging

MM Mihaylova, A Chaix, M Delibegovic, JJ Ramsey… - Cell metabolism, 2023 - cell.com
An epidemic of obesity has affected large portions of the world, increasing the risk of
developing many different age-associated diseases, including cancer, cardiovascular …

The neurovascular unit and systemic biology in stroke—implications for translation and treatment

S Tiedt, AM Buchan, M Dichgans, I Lizasoain… - Nature Reviews …, 2022 - nature.com
Ischaemic stroke is a leading cause of disability and death for which no acute treatments
exist beyond recanalization. The development of novel therapies has been repeatedly …

Intermittent fasting and time-restricted eating role in dietary interventions and precision nutrition

GA Soliman - Frontiers in public health, 2022 - frontiersin.org
Intermittent fasting (IF), time-restricted eating (TRE) and fasting-mimicking diets (FMD) are
gaining popularity as weight loss programs. As such, the timing and frequency of meals …

Nutrition strategies promoting healthy aging: From improvement of cardiovascular and brain health to prevention of age-associated diseases

M Fekete, Z Szarvas, V Fazekas-Pongor, A Feher… - Nutrients, 2022 - mdpi.com
Background: An increasing number of studies suggest that diet plays an important role in
regulating aging processes and modulates the development of the most important age …

Diet and exercise in NAFLD/NASH: beyond the obvious

G Semmler, C Datz, T Reiberger… - Liver International, 2021 - Wiley Online Library
Lifestyle represents the most relevant factor for non‐alcoholic fatty liver disease (NAFLD) as
the hepatic manifestation of the metabolic syndrome. Although a tremendous body of clinical …

Effects of anti-aging interventions on intestinal microbiota

Y Du, Y Gao, B Zeng, X Fan, D Yang, M Yang - Gut Microbes, 2021 - Taylor & Francis
Identifying ways to deal with the challenges presented by aging is an urgent task, as we are
facing an aging society. External factors such as diet, exercise and drug therapy have …

Intermittent fasting improves hepatic end points in nonalcoholic fatty liver disease: A systematic review and meta-analysis

M Lange, D Nadkarni, L Martin… - Hepatology …, 2023 - journals.lww.com
Methods: MEDLINE, EMBASE, Cochrane Central, and conference abstracts were searched
for IF interventions in adults with NAFLD until April 2, 2023. Meta-analysis with a random …

Impact of Geroscience on Therapeutic Strategies for Older Adults With Cardiovascular Disease: JACC Scientific Statement

DE Forman, GA Kuchel, JC Newman… - Journal of the American …, 2023 - jacc.org
Geroscience posits that cardiovascular disease (CVD) and other chronic diseases result
from progressive erosion of the effectiveness of homeostatic mechanisms that oppose age …