Chronic inflammation is a component of many disease conditions that affect a large group of
individuals worldwide. Chronic inflammation is characterized by persistent, low-grade …

Neutrophils are the most abundant circulating leukocytes, being the first line of defence
against bacterial and fungal infections. However, neutrophils also contribute to tissue …

Following fifteen years of research, neutrophil extracellular traps (NETs) are widely reported
in a large range of inflammatory infectious and non-infectious diseases. Cumulating …

This review describes targeting neutrophils as a potential therapeutic strategy for acute
respiratory distress syndrome (ARDS) associated with coronavirus disease 2019 (COVID …

Under normal conditions, neutrophils are restricted from trafficking into the brain
parenchyma and cerebrospinal fluid by the presence of the brain–blood barrier (BBB). Yet …

Neutrophils (polymorphonuclear cells; PMNs) form a first line of defense against pathogens
and are therefore an important component of the innate immune response. As a result of …

Neutrophil recruitment is not only vital for host defense, but also relevant in pathological
inflammatory reactions, such as sepsis. Model systems have been established to examine …

Neutrophils are the most abundant circulating and first-responding innate myeloid cells and
have so far been underestimated in the context of multiple sclerosis (MS). MS is the most …

Numerous studies suggest that neutrophils might have a crucial role in the pathogenesis of
systemic autoimmune diseases through neutrophil extracellular trap (NET) formation …

Autoimmune diseases (AiDs) are characterized by the destruction of host tissues by the host
immune system. The etiology of AiDs is complex, with the implication of multiple genetic …