Heavy metal removal by bioaccumulation using genetically engineered microorganisms

P Diep, R Mahadevan, AF Yakunin - Frontiers in bioengineering and …, 2018 - frontiersin.org
Wastewater effluents from mines and metal refineries are often contaminated with heavy
metal ions, so they pose hazards to human and environmental health. Conventional …

Synthetic biology to access and expand nature's chemical diversity

MJ Smanski, H Zhou, J Claesen, B Shen… - Nature Reviews …, 2016 - nature.com
Bacterial genomes encode the biosynthetic potential to produce hundreds of thousands of
complex molecules with diverse applications, from medicine to agriculture and materials …

[HTML][HTML] Artificial cells: from basic science to applications

C Xu, S Hu, X Chen - Materials Today, 2016 - Elsevier
Artificial cells have attracted much attention as substitutes for natural cells. There are many
different forms of artificial cells with many different definitions. They can be integral biological …

Advances and prospects of Bacillus subtilis cellular factories: from rational design to industrial applications

Y Gu, X Xu, Y Wu, T Niu, Y Liu, J Li, G Du, L Liu - Metabolic engineering, 2018 - Elsevier
Bacillus subtilis is the most characterized gram-positive bacterium that has significant
attributes, such as growing well on cheap carbon sources, possessing clear inherited …

A versatile active learning workflow for optimization of genetic and metabolic networks

A Pandi, C Diehl, A Yazdizadeh Kharrazi… - Nature …, 2022 - nature.com
Optimization of biological networks is often limited by wet lab labor and cost, and the lack of
convenient computational tools. Here, we describe METIS, a versatile active machine …

Genetically encoded biosensors for microbial synthetic biology: from conceptual frameworks to practical applications

W Yu, X Xu, K Jin, Y Liu, J Li, G Du, X Lv, L Liu - Biotechnology Advances, 2023 - Elsevier
Genetically encoded biosensors are the vital components of synthetic biology and metabolic
engineering, as they are regarded as powerful devices for the dynamic control of genotype …

Manipulating bacterial communities by in situ microbiome engineering

RU Sheth, V Cabral, SP Chen, HH Wang - Trends in Genetics, 2016 - cell.com
Microbial communities inhabit our entire planet and have a crucial role in biogeochemical
processes, agriculture, biotechnology, and human health. Here, we argue that 'in situ …

Resource competition shapes the response of genetic circuits

Y Qian, HH Huang, JI Jiménez… - ACS synthetic …, 2017 - ACS Publications
A common approach to design genetic circuits is to compose gene expression cassettes
together. While appealing, this modular approach is challenged by the fact that expression …

Design of synthetic bacterial biosensors

AJ Chiang, J Hasty - Current Opinion in Microbiology, 2023 - Elsevier
Novel whole-cell bacterial biosensor designs require an emphasis on moving toward field
deployment. Many current sensors are characterized under specified laboratory conditions …

Engineered integrative and conjugative elements for efficient and inducible DNA transfer to undomesticated bacteria

JAN Brophy, AJ Triassi, BL Adams, RL Renberg… - Nature …, 2018 - nature.com
Engineering microorganisms to promote human or plant health will require manipulation of
robust bacteria that are capable of surviving in harsh, competitive environments. Genetic …