Heart failure is a consequence of various cardiovascular diseases and associated with poor
prognosis. Despite progress in the treatment of heart failure in the past decades, prevalence …

Once myocardium dies during a heart attack, it is replaced by scar tissue over the course of
several weeks. The size, location, composition, structure and mechanical properties of the …

Myocardial infarction (MI) is the most frequent cause of heart failure, which is an
incapacitating disease with high prevalence and broad socioeconomic impact. In 2008 in …

Herein, we describe a method for targeting to and retaining intravenously (IV) injected
nanoparticles at the site of acute myocardial infarction (MI) in a rat model. Enzyme …

The zebrafish heart has the capacity to regenerate after ventricular resection. Although this
regeneration model has proved useful for the elucidation of certain regeneration …

Despite the success of current therapies for acute myocardial infarction (MI), many patients
still develop adverse cardiac remodeling and heart failure. With the growing prevalence of …

Despite current standard of care, the average 5-year mortality after an initial diagnosis of
heart failure (HF) is about 40%, reflecting an urgent need for new therapeutic approaches …

Aims After myocardial infarction (MI), injured cardiomyocytes recruit neutrophils and
monocytes/macrophages to myocardium, which in turn initiates inflammatory and reparative …

Inhibition of mitochondrial permeability transition pore (mPTP) opening by cyclosporin A or
ischemic postconditioning attenuates lethal reperfusion injury. Its impact on major post …

Background—We used a molecular probe activated by protease cleavage to image
expression of matrix metalloproteinases (MMPs) in the heart after myocardial infarction …