Our sense of hearing enables the processing of stimuli that differ in sound pressure by more
than six orders of magnitude. How to process a wide range of stimulus intensities with …

Within 1 millisecond of action potential arrival at presynaptic terminals voltage–gated Ca2+
channels open. The Ca2+ channels are linked to synaptic vesicles which are tethered by …

Cells assemble macromolecular complexes into scaffoldings that serve as substrates for
catalytic processes. Years of molecular neurobiology research indicate that …

Synaptic vesicles dock and fuse at the presynaptic active zone (AZ), the specialized site for
transmitter release. AZ proteins play multiple roles such as recruitment of Ca 2+ channels as …

Background Genetic variation in the TCF4 (transcription factor 4) gene is associated with risk
for a variety of developmental and psychiatric conditions, which includes a syndromic form of …

Background and Objectives Despite notable advances in genetic understanding of stroke
recovery, most studies focus only on candidate genes. To date, only 2 genome-wide …

An action potential triggers neurotransmitter release from synaptic vesicles docking to a
specialized release site of the presynaptic plasma membrane, the active zone. The active …

Bruxism is a worldwide oral health problem. Although there is a consensus about its
multifactorial nature, its precise etiopathogenetic mechanisms are unclear. This study, taking …

Synapses are junctions between a presynaptic neuron and a postsynaptic cell specialized
for fast and precise information transfer. The presynaptic terminal secretes neurotransmitters …

Neural diversity can expand the encoding capacity of a circuitry. A striking example of
diverse structure and function is presented by the afferent synapses between inner hair cells …