Parkinson's disease is a chronic neurodegenerative disorder characterized by the motor
symptoms of bradykinesia, tremor, rigidity and postural instability. However, non-motor …

There is now evidence that depression, as characterized by melancholic symptoms, anxiety,
and fatigue and somatic (F&S) symptoms, is the clinical expression of peripheral cell …

The amygdala exhibits significant pathological changes in Parkinson's disease, including
atrophy and Lewy body (LB) formation. Amygdala pathology has been suggested to …

In early 1920s, tyramine oxidase was discovered that metabolized tyramine and in 1933
Blaschko demonstrated that this enzyme also metabolized adrenaline, noradrenaline and …

This review examines the frequency of depression complicating Parkinson's disease (PD),
its aetiology and clinical features, and also how it may be recognised and treated. Studies …

The purpose of this review was to examine the different treatment approaches for persons
with Parkinson's Disease (PD) and to examine the effects of these treatments on speech …

Parkinson's disease (PD) is a progressive neurological condition with debilitating symptoms,
and depression is a common comorbid condition of this disease. The authors review existing …

This study investigated whether abnormalities in serotonin transporter binding occur in
Parkinson's disease (PD) patients with concurrent depression. We estimated serotonin …

The objective of this study was to determine effect sizes for both antidepressant treatment
and placebo for depression in Parkinson's disease (PD), and to compare the findings with …

The expressive mask of Parkinson's disease, a reduced spontaneity, intensity, and fluidity of
facial, bodily, and vocal expression, jeopardizes interpersonal interaction and quality of life …