The impact of aging on intestinal mucosal immune function and clinical applications
H Zheng, C Zhang, Q Wang, S Feng, Y Fang… - Frontiers in …, 2022 - frontiersin.org
Immune cells and immune molecules in the intestinal mucosa participate in innate and
adaptive immunity to maintain local and systematic homeostasis. With aging, intestinal …
adaptive immunity to maintain local and systematic homeostasis. With aging, intestinal …
[HTML][HTML] 白介素在溃疡性结肠炎发病机制中的研究进展
曹秀红， 张学彦， 张晓娜 - 世界华人消化杂志, 2011 - wjgnet.com
溃疡性结肠炎(ulcerative colitis, UC) 是一种慢性, 非特异性炎症性肠病. UC
活动性的评估结果可指导临床制订治疗方案. 因此寻找有足够的特异性和灵敏度并易于监测UC …
活动性的评估结果可指导临床制订治疗方案. 因此寻找有足够的特异性和灵敏度并易于监测UC …
Protective effect of Limosilactobacillus fermentum HFY06 on dextran sulfate sodium-induced colitis in mice
B Liu, L Yang, Y Wu, X Zhao - Frontiers in Microbiology, 2022 - frontiersin.org
Ulcerative colitis is one of the main gastrointestinal diseases that threaten human health.
This study investigated the effect of Limosilactobacillus fermentum HFY06 (LF-HFY06) on …
This study investigated the effect of Limosilactobacillus fermentum HFY06 (LF-HFY06) on …
Rho-A prenylation and signaling link epithelial homeostasis to intestinal inflammation
Although defects in intestinal barrier function are a key pathogenic factor in patients with
inflammatory bowel diseases (IBDs), the molecular pathways driving disease-specific …
inflammatory bowel diseases (IBDs), the molecular pathways driving disease-specific …
Sphingosine kinase 1 is regulated by peroxisome proliferator-activated receptor α in response to free fatty acids and is essential for skeletal muscle interleukin-6 …
We previously demonstrated that sphingosine kinase 1 (Sphk1) expression and activity are
up-regulated by exogenous palmitate (PAL) in a skeletal muscle model system and in diet …
up-regulated by exogenous palmitate (PAL) in a skeletal muscle model system and in diet …
[HTML][HTML] RNA Purity, Real-Time PCR sensitivity, and colon segment influence mRNA relative expression in murine dextran sodium sulfate experimental colitis
B Oldak, M Cruz-Rivera, A Flisser… - Journal of Biomolecular …, 2018 - ncbi.nlm.nih.gov
The dextran sodium sulfate (DSS) model of colitis is widely used as a result of its simplicity
and reproducibility and because it mimics clinicopathological disease features. Its …
and reproducibility and because it mimics clinicopathological disease features. Its …
Immunological responsiveness of intestinal tissue explants and mucosal mononuclear cells to ex vivo stimulation
RM Brand, N Biswas, A Siegel, A Myerski… - Journal of …, 2018 - Elsevier
Background There are limited data on the immunological responsiveness of healthy
intestinal tissue when it is cultured and stimulated ex vivo. Such an ex vivo model has the …
intestinal tissue when it is cultured and stimulated ex vivo. Such an ex vivo model has the …
[HTML][HTML] 基于网络药理学的黄芩汤治疗溃疡性结肠炎的潜在机制研究
宋红新， 马旭冉， 王敦方， 王彦礼， 邹迪新， 苗金雪… - 药学学报, 2020 - html.rhhz.net
利用网络药理学和系统生物学方法探究黄芩汤治疗溃疡性结肠炎(ulcerative colitis, UC)
分子机制. 从中药系统药理学分析平台TCMSP 挖掘黄芩汤中4 味中药相关的化学成分和作用靶 …
分子机制. 从中药系统药理学分析平台TCMSP 挖掘黄芩汤中4 味中药相关的化学成分和作用靶 …