Machine Learning holds promise for actionable decision support in trauma science, but
rigorous proof-of-concept studies are urgently needed. Future research should assess …

COVID-19 is linked to endotheliopathy and coagulopathy, which can result in multi-organ
failure. The mechanisms causing endothelial damage due to severe acute respiratory …

Introduction While numerous randomized controlled trials (RCTs) have been conducted in
the field of trauma, a substantial portion of them are yielding negative results. One potential …

Background In trauma systems, criteria for individualised and optimised administration of
tranexamic acid (TXA), an antifibrinolytic, are yet to be established. This study used …

Isolated traumatic spinal cord injury (t-SCI) and traumatic brain injury (TBI) represent
significant public health concerns, resulting in long-term disabilities and necessitating …

Recent advances on trauma management from the prehospital setting to in hospital care led
to a better surviving severe trauma rate. Mortality from exsanguination remains the first …

BACKGROUND Trauma-related deaths and posttraumatic sequelae are a global health
concern, necessitating a deeper understanding of the pathophysiology to advance trauma …

Disclaimer In an effort to expedite the publication of articles, AJHP is posting manuscripts
online as soon as possible after acceptance. Accepted manuscripts have been peer …

Each patient with a critical illness such as sepsis and severe trauma has a different genetic
background, comorbidities, age, and sex. Moreover, pathophysiology changes dynamically …

Recent advancements in proteomics allow for the concurrent identification and quantification
of multiple proteins. This study aimed to identify proteins associated with severe burn …