Genome data have revealed great variation in the numbers of genes in different organisms,
which indicates that there is a fundamental process of genome evolution: the origin of new …

The sex chromosomes of mammalian spermatocytes form a specialized nuclear territory
known as the XY body, where both transcription and homologous recombination are …

During meiotic prophase in male mammals, the X and Y chromosomes condense to form a
macrochromatin body, termed the sex, or XY, body, within which X-and Y-linked genes are …

During spermatogenesis, global nucleosome removal occurs where histones are initially
replaced by transition proteins and subsequently by protamines. This chromatin …

Recent cell biological observations have provided new insights into how transcription, pre-
mRNA splicing and 3′ processing are organized and coordinated with each other in the …

We have examined expression during spermatogenesis in the mouse of three Y-linked
genes, 11 X-linked genes and 22 autosomal genes, all previously shown to be germ-cell …

Besides the established central role of poly (ADP-ribose) polymerase-1 (Parp-1) and Parp-2
in the maintenance of genomic integrity, accumulating evidence indicates that poly (ADP …

Retrogenes originate from their progenitor genes by retroposition. Several retrogenes
reported in recent studies are autosomal, originating from X-linked progenitor genes, and …

Herpes simplex virus type 1 infection results in a reorganization of antigens associated with
the small nuclear ribonucleoprotein particles (snRNPs), resulting in the formation of …

X chromosome inactivation occurs twice during the life cycle of placental mammals. In
normal females, one X chromosome in each cell is inactivated early in embryogenesis, while …