Chronic neurodegenerative consequences of traumatic brain injury

NB Chauhan - Restorative neurology and neuroscience, 2014 - content.iospress.com
Traumatic brain injury (TBI) is a serious public health concern and a major cause of death
and disability worldwide. Each year, an estimated 1.7 million Americans sustain TBI of …

Prehospital and emergency care in adult patients with acute traumatic brain injury

I Pélieu, C Kull, B Walder - Medical Sciences, 2019 - mdpi.com
Traumatic brain injury (TBI) is a major healthcare problem and a major burden to society.
The identification of a TBI can be challenging in the prehospital setting, particularly in elderly …

The rich get richer: brain injury elicits hyperconnectivity in core subnetworks

FG Hillary, SM Rajtmajer, CA Roman, JD Medaglia… - PloS one, 2014 - journals.plos.org
There remains much unknown about how large-scale neural networks accommodate
neurological disruption, such as moderate and severe traumatic brain injury (TBI). A primary …

Post-traumatic seizures and antiepileptic therapy as predictors of the functional outcome in patients with traumatic brain injury

V Pingue, C Mele, A Nardone - Scientific reports, 2021 - nature.com
Post-traumatic seizures (PTS) are a common and debilitating complication of traumatic brain
injury (TBI) and could have a harmful impact on the progress of patient rehabilitation. To …

Analysis of long-term (median 10.5 years) outcomes in children presenting with traumatic brain injury and an initial Glasgow Coma Scale score of 3 or 4

DH Fulkerson, IK White, JM Rees… - Journal of …, 2015 - thejns.org
OBJECT Patients with traumatic brain injury (TBI) with low presenting Glasgow Coma Scale
(GCS) scores have very high morbidity and mortality rates. Neurosurgeons may be faced …

Influence of the initial level of consciousness on early, goal-directed mobilization: a post hoc analysis

SJ Schaller, FT Scheffenbichler, S Bose, N Mazwi… - Intensive care …, 2019 - Springer
Purpose Early mobilization within 72 h of intensive care unit (ICU) admission improves
functional status at hospital discharge. We aimed to assess the effectiveness of early, goal …

Lutein protects against severe traumatic brain injury through anti‑inflammation and antioxidative effects via ICAM‑1/Nrf‑2

D Tan, X Yu, M Chen, J Chen… - Molecular Medicine …, 2017 - spandidos-publications.com
Many studies have reported that lutein may exert its biological activities, including anti‑
inflammation, anti‑oxidase and anti‑apoptosis, through effects on reactive oxygen species …

Prehospital risk factors of mortality and impaired consciousness after severe traumatic brain injury: an epidemiological study

S Tohme, C Delhumeau, M Zuercher, G Haller… - Scandinavian journal of …, 2014 - Springer
Background Severe traumatic brain injury (TBI) is a significant health concern and a major
burden for society. The period between trauma event and hospital admission in an …

The predictive value of the Verbal Glasgow Coma Scale in traumatic brain injury: a systematic review

F Pisano, F Bilotta - The Journal of Head Trauma Rehabilitation, 2024 - journals.lww.com
Background: Traumatic brain injury (TBI) is a major global health concern, imposing
significant burdens on individuals and healthcare systems. The Glasgow Coma Scale …

Serum total cholinesterase activity on admission is associated with disease severity and outcome in patients with traumatic brain injury

QH Zhang, AM Li, SL He, XD Yao, J Zhu, ZW Zhang… - PloS one, 2015 - journals.plos.org
Background Traumatic brain injury (TBI) is one of the leading causes of neurological
disability. In this retrospective study, serum total cholinesterase (ChE) activities were …