Ferroptosis is a kind of iron-dependent regulatory necrosis characterized by the fatal
accumulation of iron-dependent lipid peroxides in the plasma membrane and the final …

Vildagliptin is a representative of Dipeptidyl Peptidase-4 (DPP-4) inhibitors,
antihyperglycemic drugs, approved for use as monotherapy and combination therapy in type …

Chronic hyperglycemic damage is a major problem that undermines diabetic wound
healing. By combining treatment and diagnosis together, blood glucose concentration can …

N-methyl-D-aspartate receptors (NMDARs) are ligand-gated, voltage-dependent channels
of the ionotropic glutamate receptor family. The present study explored whether NMDAR …

Background Inflammation plays a prominent role in the pathogenesis and progression of
acute ischemic stroke (AIS). The red blood cell distribution width to platelet ratio (RPR) has …

The inhibition of dipeptidyl peptidase-4 (DPP4) significantly enhances the wound closure
rate in diabetic patients with chronic foot ulcers. DPP4 inhibitors are only prescribed for …

The detrimental effect of hyperglycemia and glucose variability (GV) on target organs in
diabetes can be implemented through a wide network of regulatory peptides. In this study …

Objective Blood glucose is related to early neurological deterioration in acute ischemic
stroke, but multiple mechanisms are involved in early neurological deterioration, such as …

Background and purpose: Early neurological deterioration (END) is associated with poor
outcome for patients with acute ischemic stroke (AIS). Patients with hyperglycemia have …

Osteoarthritis (OA) is a common age‐related disorder. Chondrocytes in joint tissue play a
critical role in normal articular cartilage function and tissue homeostasis. Local inflammatory …