A meta-analysis of ultra-high field glutamate, glutamine, GABA and glutathione 1HMRS in psychosis: Implications for studies of psychosis risk
Ultra-high field proton magnetic resonance spectroscopy (1 HMRS) offers a unique
opportunity to measure the concentration of neurometabolites implicated in psychosis (PSY) …
opportunity to measure the concentration of neurometabolites implicated in psychosis (PSY) …
Decrypting UFMylation: how proteins are modified with UFM1
Besides ubiquitin (Ub), humans have a set of ubiquitin-like proteins (UBLs) that can also
covalently modify target proteins. To date, less is known about UBLs than Ub and even less …
covalently modify target proteins. To date, less is known about UBLs than Ub and even less …
The ubiquitin proteasome system and schizophrenia
The ubiquitin-proteasome system is a master regulator of neural development and the
maintenance of brain structure and function. It influences neurogenesis, synaptogenesis …
maintenance of brain structure and function. It influences neurogenesis, synaptogenesis …
UFMylation: a unique & fashionable modification for life
Y Wei, X Xu - Genomics, Proteomics and Bioinformatics, 2016 - academic.oup.com
Abstract Ubiquitin-fold modifier 1 (UFM1) is one of the newly-identified ubiquitin-like
proteins. Similar to ubiquitin, UFM1 is conjugated to its target proteins by a three-step …
proteins. Similar to ubiquitin, UFM1 is conjugated to its target proteins by a three-step …
Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoids
De novo mutations and copy number deletions in NRXN1 (2p16. 3) pose a significant risk for
schizophrenia (SCZ). It is unclear how NRXN1 deletions impact cortical development in a …
schizophrenia (SCZ). It is unclear how NRXN1 deletions impact cortical development in a …
An integrative tissue-network approach to identify and test human disease genes
Effective discovery of causal disease genes must overcome the statistical challenges of
quantitative genetics studies and the practical limitations of human biology experiments …
quantitative genetics studies and the practical limitations of human biology experiments …
The endoplasmic reticulum stress response in neuroprogressive diseases: emerging pathophysiological role and translational implications
The endoplasmic reticulum (ER) is the main cellular organelle involved in protein synthesis,
assembly and secretion. Accumulating evidence shows that across several …
assembly and secretion. Accumulating evidence shows that across several …
[HTML][HTML] A sentinel in the crosstalk between the nervous and immune system: the (immuno)-proteasome
F Limanaqi, F Biagioni, A Gaglione, CL Busceti… - Frontiers in …, 2019 - frontiersin.org
The wealth of recent evidence about a bi-directional communication between nerve-and
immune-cells revolutionized the traditional concept about the brain as an “immune …
immune-cells revolutionized the traditional concept about the brain as an “immune …
The ufm1 cascade
J Daniel, E Liebau - Cells, 2014 - mdpi.com
The ubiquitin-fold modifier 1 (Ufm1) is a posttranslational modifier that belongs to the
ubiquitin-like protein (UBL) family. Ufm1 is present in nearly all eukaryotic organisms, with …
ubiquitin-like protein (UBL) family. Ufm1 is present in nearly all eukaryotic organisms, with …
Genome‐wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study
The genetic basis of sleep is still poorly understood. Despite the moderate to high heritability
of sleep‐related phenotypes, known genetic variants explain only a small proportion of the …
of sleep‐related phenotypes, known genetic variants explain only a small proportion of the …