The human interferon-inducible IFI16 protein, an innate immune sensor of intracellular DNA,
was recently demonstrated to act as a restriction factor for human cytomegalovirus (HCMV) …

Papillomaviruses (PV) have a wide distribution of hosts, among which human
papillomavirus (HPV) has been recognized as the major cause of cervical cancer. HPV is …

Viruses manipulate the cell cycle of the host cell to optimize conditions for more efficient viral
genome replication. One strategy utilized by DNA viruses is to replicate their genomes non …

High-risk HPV (hrHPV) is the leading etiologic factor in oropharyngeal cancer. HPV-positive
oropharyngeal tumors generally respond well to therapy, with complete recovery in …

HPV16 is the most oncogenic type of human papillomaviruses (HPV). Integration of HPV into
the human genome is an important mechanism of carcinogenesis but is absent in at least …

The papillomavirus E2 protein executes numerous essential functions related to viral
transcription, replication of viral DNA, and viral genome maintenance. Because E2 lacks …

Betapapillomavirus replication and transcription have not been studied in detail because of
a lack of suitable cellular systems supporting human papillomavirus (HPV) genome …

The life-cycle of human papillomaviruses (HPVs) includes three distinct phases of the viral
genome replication. First, the viral genome is amplified in the infected cells, and this …

The human papillomavirus (HPV) vaccines hold great promise for preventing several
cancers caused by HPV infections. Yet little attention has been given to whether HPV could …

Inhibition of human papillomavirus (HPV) replication is a promising therapeutic approach for
intervening with HPV-related pathologies. Primary targets for interference are two viral …