Biology and therapeutic targeting of vascular endothelial growth factor A
L Pérez-Gutiérrez, N Ferrara - Nature Reviews Molecular Cell Biology, 2023 - nature.com
The formation of new blood vessels, called angiogenesis, is an essential pathophysiological
process in which several families of regulators have been implicated. Among these, vascular …
process in which several families of regulators have been implicated. Among these, vascular …
Cationic, anionic and neutral polysaccharides for skin tissue engineering and wound healing applications
Today, chronic wound care and management can be regarded as a clinically critical issue.
However, the limitations of current approaches for wound healing have encouraged …
However, the limitations of current approaches for wound healing have encouraged …
[HTML][HTML] Single-cell transcriptome atlas of murine endothelial cells
The heterogeneity of endothelial cells (ECs) across tissues remains incompletely
inventoried. We constructed an atlas of> 32,000 single-EC transcriptomes from 11 mouse …
inventoried. We constructed an atlas of> 32,000 single-EC transcriptomes from 11 mouse …
Exosome‐guided phenotypic switch of M1 to M2 macrophages for cutaneous wound healing
Macrophages (Mϕs) critically contribute to wound healing by coordinating inflammatory,
proliferative, and angiogenic processes. A proper switch from proinflammatory M1 to anti …
proliferative, and angiogenic processes. A proper switch from proinflammatory M1 to anti …
The blood–brain barrier
R Daneman, A Prat - Cold Spring Harbor perspectives in …, 2015 - cshperspectives.cshlp.org
Blood vessels are critical to deliver oxygen and nutrients to all of the tissues and organs
throughout the body. The blood vessels that vascularize the central nervous system (CNS) …
throughout the body. The blood vessels that vascularize the central nervous system (CNS) …
Macrophage-induced blood vessels guide Schwann cell-mediated regeneration of peripheral nerves
AL Cattin, JJ Burden, L Van Emmenis, FE Mackenzie… - Cell, 2015 - cell.com
The peripheral nervous system has remarkable regenerative capacities in that it can repair a
fully cut nerve. This requires Schwann cells to migrate collectively to guide regrowing axons …
fully cut nerve. This requires Schwann cells to migrate collectively to guide regrowing axons …
The roles of vascular endothelial growth factor in bone repair and regeneration
K Hu, BR Olsen - Bone, 2016 - Elsevier
Vascular endothelial growth factor-A (VEGF) is one of the most important growth factors for
regulation of vascular development and angiogenesis. Since bone is a highly vascularized …
regulation of vascular development and angiogenesis. Since bone is a highly vascularized …
Vascular permeability in diseases
JL Wautier, MP Wautier - International Journal of Molecular Sciences, 2022 - mdpi.com
Vascular permeability is a selective mechanism that maintains the exchange between
vessels, tissues, and organs. The regulation was mostly studied during the nineteenth …
vessels, tissues, and organs. The regulation was mostly studied during the nineteenth …
Osteoblast-derived VEGF regulates osteoblast differentiation and bone formation during bone repair
K Hu, BR Olsen - The Journal of clinical investigation, 2016 - Am Soc Clin Investig
Osteoblast-derived VEGF is important for bone development and postnatal bone
homeostasis. Previous studies have demonstrated that VEGF affects bone repair and …
homeostasis. Previous studies have demonstrated that VEGF affects bone repair and …
Exosomes from hypoxia-treated human adipose-derived mesenchymal stem cells enhance angiogenesis through VEGF/VEGF-R
Y Han, J Ren, Y Bai, X Pei, Y Han - … journal of biochemistry & cell biology, 2019 - Elsevier
Background We previously reported that co-transplantation of exosomes from hypoxia-
preconditioned adipose mesenchymal stem cells (ADSCs) improves the neoangiogenesis …
preconditioned adipose mesenchymal stem cells (ADSCs) improves the neoangiogenesis …