Cannabis, or marijuana, has been used for centuries for both symptomatic and prophylactic
treatment of migraine. It was highly esteemed as a headache remedy by the most prominent …

Nutrition must affect the structure and functioning of the brain. Since the brain has very high
metabolic activity, what we consume throughout the day is likely to dramatically influence …

Cannabidiol (CBD) is a major, biologically active, but psycho-inactive component of
cannabis. In this cell culture-based report, CBD is shown to displace the agonist,[3H] 8-OH …

Nitric oxide (NO) generated from inducible NO synthase (iNOS) participates in immune and
inflammatory responses in many tissues. The NO donor glyceryl trinitrate (GTN) provokes …

A series of aminoparthenolide analogs have been synthesized through a diastereoselective
conjugate addition of several primary and secondary amines to the α-methylene-γ …

Aqueous and ethanolic extracts of 42 plants used in Danish folk medicine for the treatment
of epilepsy and convulsions, or for inducing sedation, were tested for affinity to the GABAA …

Parthenolide, a sesquiterpene lactone, has been reported to exhibit a variety of anti-
inflammatory and immunomodulatory effects. To test the effect of parthenolide on brain …

Extracts of Tanacetum parthenium are used in the prophylactic treatment of migraine and
have also been used in Danish folk medicine for the treatment of epilepsy. An ethanol …

Diabetes is associated with behavioural and neurochemical alterations. In this manuscript,
we are reporting the beneficial effects of parthenolide, an NF-κB inhibitor on behavioural …

Background: Tanacetum parthenium (feverfew) has been used traditionally to treat migraine,
and although its mechanism of action is not fully understood, serotonin 5-HT receptor …