As an essential micronutrient, manganese (Mn) participates in various physiological
processes and plays important roles in host immune system, hematopoiesis, endocrine …

Immunotherapy has efficiently revolutionized the treatment of human neoplastic diseases.
However, the overall responsive rate of current immunotherapy is still unsatisfactory …

Immunotherapy has attracted widespread attention in cancer treatment and has achieved
considerable success in the clinical treatment of some tumors, but it has a low response rate …

Chemodynamic therapy (CDT), as an emerging therapeutic strategy, kills cancer cells by
converting intracellular hydrogen peroxide (H 2 O 2) into cytotoxic oxidizing hydroxyl …

As the first line of host defense against pathogenic infections, innate immunity plays a key
role in antitumor immunotherapy. The cyclic GMP‐AMP synthase (cGAS)‐stimulator of …

Tumor immunotherapy as a new tumor therapy has been intensively studied and reported.
However, the expected utilization and therapeutic effects have not been achieved due to the …

Brain disorders represent a significant challenge in medical science due to the formidable
blood–brain barrier (BBB), which severely limits the penetration of conventional …

The desmoplastic stroma imposes a fatal physical delivery barrier in pancreatic ductal
adenocarcinoma (PDAC) therapy. Deconstructing the stroma components hence …

Cancer is a complex disease associated with a combination of abnormal physiological
process and exhibiting dysfunctions in multiple systems. To provide effective treatment and …

Breast cancer has a high occurrence rate globally and its treatment has demonstrated
clinical efficacy with the use of systemic chemotherapy and immune checkpoint blockade …