[HTML][HTML] Neuropathic pain: mechanisms, sex differences, and potential therapies for a global problem
S Ghazisaeidi, MM Muley… - Annual Review of …, 2023 - annualreviews.org
The study of chronic pain continues to generate ever-increasing numbers of publications,
but safe and efficacious treatments for chronic pain remain elusive. Recognition of sex …
but safe and efficacious treatments for chronic pain remain elusive. Recognition of sex …
Rheumatoid arthritis and depression: an inflammatory perspective
L Nerurkar, S Siebert, IB McInnes… - The Lancet Psychiatry, 2019 - thelancet.com
The coexistence of immune-mediated inflammatory diseases with depression has long been
recognised. Data that illustrate the intimate associations between peripheral and brain …
recognised. Data that illustrate the intimate associations between peripheral and brain …
[HTML][HTML] The IL-1β, IL-6, and TNF cytokine triad is associated with post-acute sequelae of COVID-19
C Schultheiß, E Willscher, L Paschold, C Gottschick… - Cell Reports …, 2022 - cell.com
Post-acute sequelae of COVID-19 (PASC) is emerging as global problem with unknown
molecular drivers. Using a digital epidemiology approach, we recruited 8,077 individuals to …
molecular drivers. Using a digital epidemiology approach, we recruited 8,077 individuals to …
Etiology and pharmacology of neuropathic pain
SRA Alles, PA Smith - Pharmacological reviews, 2018 - ASPET
Injury to or disease of the nervous system can invoke chronic and sometimes intractable
neuropathic pain. Many parallel, interdependent, and time-dependent processes, including …
neuropathic pain. Many parallel, interdependent, and time-dependent processes, including …
[HTML][HTML] Gut-brain axis and migraine headache: a comprehensive review
The terminology “gut-brain axis “points out a bidirectional relationship between the GI
system and the central nervous system (CNS). To date, several researches have shown that …
system and the central nervous system (CNS). To date, several researches have shown that …
Neuropathic pain: mechanisms and their clinical implications
Neuropathic pain can develop after nerve injury, when deleterious changes occur in injured
neurons and along nociceptive and descending modulatory pathways in the central nervous …
neurons and along nociceptive and descending modulatory pathways in the central nervous …
[HTML][HTML] Exploring novel therapeutic targets in the common pathogenic factors in migraine and neuropathic pain
J Tajti, D Szok, A Csáti, Á Szabó, M Tanaka… - International Journal of …, 2023 - mdpi.com
Migraine and neuropathic pain (NP) are both painful, disabling, chronic conditions which
exhibit some symptom similarities and are thus considered to share a common etiology. The …
exhibit some symptom similarities and are thus considered to share a common etiology. The …
Antidepressants and gabapentinoids in neuropathic pain: mechanistic insights
Neuropathic pain arises as a consequence of a lesion or disease affecting the
somatosensory system. It is generally chronic and challenging to treat. The recommended …
somatosensory system. It is generally chronic and challenging to treat. The recommended …
Neuroinflammation and the generation of neuropathic pain
A Ellis, DLH Bennett - British journal of anaesthesia, 2013 - academic.oup.com
Inflammation is the process by which an organism responds to tissue injury involving both
immune cell recruitment and mediator release. Diverse causes of neuropathic pain are …
immune cell recruitment and mediator release. Diverse causes of neuropathic pain are …
[HTML][HTML] Deconstructing the neuropathic pain phenotype to reveal neural mechanisms
CA von Hehn, R Baron, CJ Woolf - Neuron, 2012 - cell.com
After nerve injury maladaptive changes can occur in injured sensory neurons and along the
entire nociceptive pathway within the CNS, which may lead to spontaneous pain or pain …
entire nociceptive pathway within the CNS, which may lead to spontaneous pain or pain …