Metal complexes are extensively used for cancer therapy. The multiple variables available
for tuning (metal, ligand, and metal–ligand interaction) offer unique opportunities for drug …

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

With nearly 10 million deaths, cancer is the leading cause of mortality worldwide. Along with
major key parameters that control cancer treatment management, such as diagnosis …

The microbiota is composed of commensal bacteria and other microorganisms that live on
the epithelial barriers of the host. The commensal microbiota is important for the health and …

Background Cisplatin (CDDP) treatment is one of the most predominant chemotherapeutic
strategies for patients with gastric cancer (GC). A better understanding of the mechanisms of …

Apoptotic cells have long been considered as intrinsically tolerogenic or unable to elicit
immune responses specific for dead cell-associated antigens. However, multiple stimuli can …

Abstract Cisplatin (cis-diammine-dichloro-platinum II) was initially discovered to prevent the
growth of Escherichia coli and was further recognized for its anti-neoplastic and cytotoxic …

Epithelial ovarian cancer (EOC) is the most lethal gynecological cancer. It is initially
responsive to cisplatin and carboplatin, two DNA damaging agents used in first line therapy …

Chemotherapy is one of the prevailing methods used to treat malignant tumours, but the
outcome and prognosis of tumour patients are not optimistic. Cancer cells gradually …

Patients with advanced or recurrent cervical cancer have poor prognosis, and their 1-year
survival is only 10%–20%. Chemotherapy is considered as the standard treatment for …