Plant virus diseases, also known as “plant cancers”, cause serious harm to the agriculture of
the world and huge economic losses every year. Antiviral agents are one of the most …

Plant virus disease is the second most prevalent plant diseases and can cause extensive
loss in global agricultural economy. Extensive work has been carried out on the …

Marine natural products have attracted more and more attention in drug research and
development due to their unique structure, diverse biological activities, and novel mode of …

On the basis of the scaffolds widely used in drug design, a series of novel spirooxindole
derivatives containing hydantoin, thiohydantoin, urea, and thiourea moieties have been …

In this study, we report the synthesis and antiviral activity of trans-ferulic acid derivatives
containing acylhydrazone moiety. Biological tests demonstrated that most target compounds …

For the first time, the botanic source natural product matrine was reported to have more
potent inhibitory activity against tobacco mosaic virus (TMV) than the commercial virucide …

1, 4-Pentadien-3-one derivatives derived from curcumin possess excellent inhibitory activity
against plant viruses. On the basis of this finding, a series of novel 1, 4-pentadien-3-one …

A series of novel 3-((2-((1 E, 4 E)-3-oxo-5-arylpenta-1, 4-dien-1-yl) phenoxy) methyl)-4 (3 H)-
quinazolinone derivatives were designed and synthesized. Antiviral bioassays indicated that …

A series of novel α-aminophosphonate derivatives containing hydrazone were designed
and synthesized based on active fragments. Bioassay results demonstrated that title …

Based on the widespread use of hydrogen bonds in drug design, a series of aldisine
derivatives containing oxime, oxime ether, and hydrazone moieties were designed and …