STUDY QUESTION What are the chances of achieving a live birth after embryo, oocyte and
ovarian tissue cryopreservation (OTC) in female cancer survivors? SUMMARY ANSWER …

Ovarian tissue cryopreservation (OTC) is the only pre-treatment option currently available to
preserve fertility for prepubescent girls and patients who cannot undergo ovarian …

Background Chemotherapeutic drugs, particularly alkylating cytotoxics such as
cyclophosphamide (CTX), play an important role to induce premature ovarian failure (POF) …

STUDY QUESTION What are the pregnancy and live birth rates for ovarian tissue
transplantation and which factors are associated with the success rate? SUMMARY …

In patients with hormone receptor–positive early-stage breast cancer, adjuvant endocrine
treatment administered for up to 5-10 years after diagnosis significantly reduces the risk of …

Poly-ADP-ribose polymerase (PARP) plays an important role in DNA damage detection and
repair. PARP inhibitors (PARPi) are a novel class of targeted agents used widely in the …

Background Ovarian tissue cryopreservation (OTC) is the only method of fertility
preservation (FP) in prepubertal girls, but the experience remains limited. This study …

STUDY QUESTION Does a matrix-free culture system supplemented with neurotrophic
factor 4 (NT4) improve human in vitro follicular development and meiotic maturation …

Abstract Since 2007, the Oncofertility Consortium Annual Conference has brought together a
diverse network of individuals from a wide range of backgrounds and professional levels to …

Background The massive loss of follicles in the early stage of ovarian tissue transplantation
is considered a significant restriction to the efficacy of ovarian tissue cryopreservation (OTC) …