Mitochondrial disease is a challenging area of genetics because two distinct genomes can
contribute to disease pathogenesis. It is also challenging clinically because of the myriad of …

Signal recognition particle (SRP) is an RNA and protein complex that exists in all domains of
life. It consists of one protein and one noncoding RNA in some bacteria. It is more complex …

Most mitochondrial proteins are synthesized on cytosolic ribosomes and imported into
mitochondria in a post-translational reaction. Mitochondrial precursor proteins which use the …

Secreted and membrane proteins represent a third of all cellular proteins and contain N-
terminal signal peptides that are required for protein targeting to endoplasmic reticulum …

The type-2 peroxisomal targeting signal (PTS2) is one of two peptide motifs destining
soluble proteins for peroxisomes. This signal acts as amphiphilic α-helix exposing the side …

Metabolism is the central engine of living organisms as it provides energy and building
blocks for many essential components of each cell, which are required for specific functions …

Microbial production of carotenoids has mainly focused towards a few products, such as β-
carotene, lycopene and astaxanthin. However, other less explored carotenoids, like …

Abstract Microsomal glutathione transferase 1 (MGST1) is a member of the MAPEG family
(membrane associated proteins in eicosanoid and glutathione metabolism), defined …

Main conclusion Transcriptome analysis of Leucojum aestivum led to the identification of 50
key genes associated with Amaryllidaceae alkaloid biosynthesis including norbelladine …

The glyoxylate cycle is essential for growth on C 2 compounds such as acetate. In this
investigation, for the first time, we have elucidated the subcellular localization of the …