Liposomes mimic natural cell membranes and have long been investigated as drug carriers
due to excellent entrapment capacity, biocompatibility and safety. Despite the success of …

Although flavonoid compounds have various pharmacological applications, they generally
exhibit low oral bioavailability due to their poor aqueous solubility. To address this problem …

Topical instillation of eye drops remains the most common and easiest route of ocular drug
administration, representing the treatment of choice for many ocular diseases. Nevertheless …

Against a backdrop of global antibiotic resistance and increasing awareness of the
importance of the human microbiota, there has been resurgent interest in the potential use of …

Tailoring of chitosan through the involvement of its amino, acetamido, and hydroxy groups
can give derivatives of enhanced solubility and remarkable anticancer activity. The general …

Abstract Background Bioactive peptides (BAPs) play a crucial physiological role in human
health. To exert their biological effects after oral administration, BAPs have to be transported …

While the peptide and protein therapeutic market has developed significantly in the past
decades, delivery has limited their use. Although oral delivery is preferred, most are …

Cancer, as one of the most life-threatening diseases, has attracted the attention of
researchers to develop drugs with minimal side effects. The bioactive macromolecules, such …

The poor oral bioavailability arising from poor aqueous solubility should make drug research
and development more difficult. Various approaches have been developed with a focus on …

Intestinal permeation enhancers (PEs) are one of the most widely tested strategies to
improve oral delivery of therapeutic peptides. This article assesses the intestinal permeation …