High blood pressure is present in more than one billion adults worldwide and is the most
important modifiable risk factor of death resulting from cardiovascular disease. While many …

Trained immunity is a process in which innate immune cells undergo functional
reprogramming in response to pathogens or damage‐associated molecules leading to an …

Uric acid is a waste product of purine catabolism. This molecule comes to clinical attention
when it nucleates to form crystals of monosodium urate (MSU) in joints or other tissues, and …

Studies have demonstrated that circulating levels of plasma cytokines are influenced greatly
by age and that chronic elevated levels of certain cytokines are associated with chronic …

Background: Physical activity has been shown to be beneficial for the prevention and
management of hypertension. In the general population, physical activity has been shown to …

Chronic inflammation in the kidneys and vascular wall is a major contributor to hypertension.
However, the stimuli and cellular mechanisms responsible for such inflammatory responses …

With cardiovascular disease (CVD) being a primary source of global morbidity and mortality,
it is crucial that we understand the molecular pathophysiological mechanisms at play …

The concept of hypertension as primarily a consequence of altered hemodynamics has
changed. Many factors are now implicated in the development of hypertensive vascular …

Arterial hypertension affects≈ 1 billion people worldwide. It is associated with increased
morbidity and mortality and responsible for millions of deaths each year. Hypertension …

Evidence that was obtained in several experimental models and in strains of hypertensive
rats indicates that infiltration of inflammatory cells and oxidative stress in the kidney play a …