With almost 20 million new cases per year, cancer constitutes one of the most important
challenges for public health systems. Unlike traditional chemotherapy, targeted anti-cancer …

Introduction Monoclonal antibodies have been utilized in clinical and basic research for the
treatment of various malignancies. Whilst all therapeutically approved monoclonal …

Abstracts Background Overexpressed PES1 promotes carcinogenesis in various types of
malignant tumors. However, the biological role and clinical significance of PES1 in …

Circular RNAs (circRNAs) are unique noncoding RNAs that have a closed and stable loop
structure generated through backsplicing. Due to their conservation, stability and tissue …

Possible association between Helicobacter pylori infection (HPI) and nonalcoholic fatty liver
disease (NAFLD) has been proposed by several studies with inconsistent conclusions …

Immunotoxin therapy is one of the immunotherapy strategies providing a new, effective and
high potency treatment against various cancers. Breast cancer is the most common cancer …

Targeting cell surface receptors with immunotoxins provides a novel, unique and highly
potent treatment against cancers. A high expression of interleukin-13 (IL13) receptor α2 …

Targeted therapy has been recently highlighted due to the reduction of side effects and
improvement in overall efficacy and survival from different types of cancers. Considering the …

The consumption of cruciferous vegetables rich in isothiocyanates has long been associated
with a reduced risk of various types of cancer. 4-(methylthio) butyl isothiocyanate also called …

Membrane proteins (MPs) are playing important roles in several biological processes.
Screening new candidate compounds targeting MPs is important for drug discovery …