Although first identified over 70 years ago, Klinefelter syndrome (KS) continues to pose
substantial diagnostic challenges, as many patients are still misdiagnosed, or remain …

Azoospermia affects 1% of men, and it can be due to:(i) hypothalamic-pituitary
dysfunction,(ii) primary quantitative spermatogenic disturbances,(iii) urogenital duct …

Approximately 7% of men suffer from fertility problems, the etiology of which are ascribable
to a number of factors acting at pretesticular, posttesticular, or testicular levels. About 20% of …

Infertility affects about 7% of all men. The etiology of impaired sperm production and function
can be related to factors acting at pre-testicular, post-testicular or directly at the testicular …

Background: Preimplantation genetic testing (PGT) is widely used today in in-vitro
fertilization (IVF) centers over the world for selecting euploid embryos for transfer and to …

Abstract Approximately 10%–15% of couples are infertile, and a male factor is involved in
almost half of these cases. This observation is due in part to defects in spermatogenesis …

Infertility is known to decrease quality of life among adults. In some cases, infertility is
caused by medical conditions and/or treatments prescribed in childhood, and using methods …

Non-Obstructive Azoospermia (NOA) affects about 1% of men in the general population and
is characterized by clinical heterogeneity implying the involvement of several different …

Male subfertility is common, and it causes significant duress to couples. Although the most
common cause of male subfertility is idiopathic failure of spermatogenesis, a significant …

Klinefelter syndrome (KS) is the most common genetic form of male hypogonadism, but overt
phenotype becomes evident only after puberty. During childhood, and even during early …