[HTML][HTML] Extracellular vesicles: the next generation theranostic nanomedicine for inflammatory bowel disease

D Li, M Yang, J Xu, H Xu, M Zhu, Y Liang… - International journal …, 2022 - ncbi.nlm.nih.gov
The recent rapid development in the field of extracellular vesicles (EVs) based
nanotechnology has provided unprecedented opportunities for nanomedicine platforms. As …

Extracellular-vesicle-based therapeutics in neuro-ophthalmic disorders

H Massoumi, S Amin, M Soleimani… - International Journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs) have been recognized as promising candidates for developing
novel therapeutics for a wide range of pathologies, including ocular disorders, due to their …

[HTML][HTML] Engineered mesenchymal stem cell-derived small extracellular vesicles for diabetic retinopathy therapy through HIF-1α/EZH2/PGC-1α pathway

F Sun, Y Sun, X Wang, J Zhu, S Chen, Y Yu, M Zhu… - Bioactive Materials, 2024 - Elsevier
Diabetic retinopathy (DR) is a leading cause of blindness worldwide with limited treatment
options. Mesenchymal stem cell-derived small extracellular vesicles (MSC-sEVs) hold …

Smart Nanoscale Extracellular Vesicles in the Brain: Unveiling their Biology, Diagnostic Potential, and Therapeutic Applications

A Onkar, F Khan, A Goenka… - … Applied Materials & …, 2024 - ACS Publications
Information exchange is essential for the brain, where it communicates the physiological and
pathological signals to the periphery and vice versa. Extracellular vesicles (EVs) are a …

Optic neuritis in multiple sclerosis—a review of molecular mechanisms involved in the degenerative process

MA Ciapă, DL Șalaru, C Stătescu, RA Sascău… - Current Issues in …, 2022 - mdpi.com
Multiple sclerosis is a central nervous system inflammatory demyelinating disease with a
wide range of clinical symptoms, ocular involvement being frequently marked by the …

Modulation of mesenchymal stem cells for enhanced therapeutic utility in ischemic vascular diseases

SL Elshaer, SH Bahram, P Rajashekar… - International Journal of …, 2021 - mdpi.com
Mesenchymal stem cells are multipotent stem cells isolated from various tissue sources,
including but not limited to bone marrow, adipose, umbilical cord, and Wharton Jelly …

hMSC exosomes as a novel treatment for female sensitive skin: An in vivo study

C Ye, Y Zhang, Z Su, S Wu, Y Li, J Yi, W Lai… - … in Bioengineering and …, 2022 - frontiersin.org
Background: Recent studies have reported that the incidence of sensitive skin is increasing.
Skin sensitivity and skin barrier functions were related to many skin diseases including …

Uncovering the genetics and physiology behind optic neuritis

I Del Negro, G Pauletto, L Verriello, L Spadea, C Salati… - Genes, 2023 - mdpi.com
Optic neuritis (ON) is an inflammatory condition affecting the optic nerve, leading to vision
impairment and potential vision loss. This manuscript aims to provide a comprehensive …

Mesenchymal stem cell-derived extracellular vesicles and their therapeutic use in central nervous system demyelinating disorders

C Allegretta, E D'Amico, V Manuti, C Avolio… - International Journal of …, 2022 - mdpi.com
Autoimmune demyelinating diseases—including multiple sclerosis, neuromyelitis optica
spectrum disorder, anti-myelin oligodendrocyte glycoprotein-associated disease, acute …

Mesenchymal Stem Cell–Derived Exosomes in Various Chronic Liver Diseases: Hype or Hope?

L Zhu, Q Wang, M Guo, H Fang, T Li, Y Zhu… - Journal of …, 2024 - Taylor & Francis
Chronic liver conditions are associated with high mortality rates and have a large adverse
effect on human well-being as well as a significant financial burden. Currently, the only …