Targeted drug delivery for cancer therapy: the other side of antibodies

MA Firer, G Gellerman - Journal of hematology & oncology, 2012 - Springer
Therapeutic monoclonal antibody (TMA) based therapies for cancer have advanced
significantly over the past two decades both in their molecular sophistication and clinical …

Antimicrobial peptides with high proteolytic resistance for combating gram-negative bacteria

J Wang, J Song, Z Yang, S He, Y Yang… - Journal of medicinal …, 2019 - ACS Publications
Poor proteolytic resistance is an urgent problem to be solved in the clinical application of
antimicrobial peptides (AMPs), yet common solutions, such as complicated chemical …

The next generation of antimicrobial peptides (AMPs) as molecular therapeutic tools for the treatment of diseases with social and economic impacts

NB da Cunha, NB Cobacho, JFC Viana, LA Lima… - Drug discovery today, 2017 - Elsevier
Highlights•Review of the present status of the development of antimicrobial peptides
(AMPs).•Recent advances in designing new anti-infective agents with enhanced …

Peptides: Production, bioactivity, functionality, and applications

M Hajfathalian, S Ghelichi… - Critical reviews in …, 2018 - Taylor & Francis
Production of peptides with various effects from proteins of different sources continues to
receive academic attention. Researchers of different disciplines are putting increasing efforts …

Compstatin: a C3‐targeted complement inhibitor reaching its prime for bedside intervention

DC Mastellos, D Yancopoulou… - European journal of …, 2015 - Wiley Online Library
There is a growing awareness that complement plays an integral role in human physiology
and disease, transcending its traditional perception as an accessory system for pathogen …

Myostatin and its regulation: a comprehensive review of myostatin inhibiting strategies

MH Baig, K Ahmad, JS Moon, SY Park… - Frontiers in …, 2022 - frontiersin.org
Myostatin (MSTN) is a well-reported negative regulator of muscle growth and a member of
the transforming growth factor (TGF) family. MSTN has important functions in skeletal muscle …

PEPstrMOD: structure prediction of peptides containing natural, non-natural and modified residues

S Singh, H Singh, A Tuknait, K Chaudhary, B Singh… - Biology direct, 2015 - Springer
Background In the past, many methods have been developed for peptide tertiary structure
prediction but they are limited to peptides having natural amino acids. This study describes a …

Combinatorial peptide libraries: mining for cell-binding peptides

BP Gray, KC Brown - Chemical reviews, 2014 - ACS Publications
The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …

Clinical applications of antimicrobial peptides (AMPs): where do we stand now?

M Divyashree, MK Mani, D Reddy… - Protein and peptide …, 2020 - ingentaconnect.com
In this era of multi-drug resistance (MDR), antimicrobial peptides (AMPs) are one of the most
promising classes of potential drug candidates to combat communicable as well as …

[HTML][HTML] LinTT1 peptide-functionalized liposomes for targeted breast cancer therapy

N d'Avanzo, G Torrieri, P Figueiredo, C Celia… - International journal of …, 2021 - Elsevier
Breast cancer, with around 2 million new cases in 2019, is the second most common cancer
worldwide and the second leading cause of cancer death among females. The aim of this …