Targeted drug delivery for cancer therapy: the other side of antibodies
MA Firer, G Gellerman - Journal of hematology & oncology, 2012 - Springer
Therapeutic monoclonal antibody (TMA) based therapies for cancer have advanced
significantly over the past two decades both in their molecular sophistication and clinical …
significantly over the past two decades both in their molecular sophistication and clinical …
Antimicrobial peptides with high proteolytic resistance for combating gram-negative bacteria
J Wang, J Song, Z Yang, S He, Y Yang… - Journal of medicinal …, 2019 - ACS Publications
Poor proteolytic resistance is an urgent problem to be solved in the clinical application of
antimicrobial peptides (AMPs), yet common solutions, such as complicated chemical …
antimicrobial peptides (AMPs), yet common solutions, such as complicated chemical …
The next generation of antimicrobial peptides (AMPs) as molecular therapeutic tools for the treatment of diseases with social and economic impacts
NB da Cunha, NB Cobacho, JFC Viana, LA Lima… - Drug discovery today, 2017 - Elsevier
Highlights•Review of the present status of the development of antimicrobial peptides
(AMPs).•Recent advances in designing new anti-infective agents with enhanced …
(AMPs).•Recent advances in designing new anti-infective agents with enhanced …
Peptides: Production, bioactivity, functionality, and applications
M Hajfathalian, S Ghelichi… - Critical reviews in …, 2018 - Taylor & Francis
Production of peptides with various effects from proteins of different sources continues to
receive academic attention. Researchers of different disciplines are putting increasing efforts …
receive academic attention. Researchers of different disciplines are putting increasing efforts …
Compstatin: a C3‐targeted complement inhibitor reaching its prime for bedside intervention
DC Mastellos, D Yancopoulou… - European journal of …, 2015 - Wiley Online Library
There is a growing awareness that complement plays an integral role in human physiology
and disease, transcending its traditional perception as an accessory system for pathogen …
and disease, transcending its traditional perception as an accessory system for pathogen …
Myostatin and its regulation: a comprehensive review of myostatin inhibiting strategies
Myostatin (MSTN) is a well-reported negative regulator of muscle growth and a member of
the transforming growth factor (TGF) family. MSTN has important functions in skeletal muscle …
the transforming growth factor (TGF) family. MSTN has important functions in skeletal muscle …
PEPstrMOD: structure prediction of peptides containing natural, non-natural and modified residues
Background In the past, many methods have been developed for peptide tertiary structure
prediction but they are limited to peptides having natural amino acids. This study describes a …
prediction but they are limited to peptides having natural amino acids. This study describes a …
Combinatorial peptide libraries: mining for cell-binding peptides
BP Gray, KC Brown - Chemical reviews, 2014 - ACS Publications
The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …
a unique cellular landscape specific to the type and state of the cell. Ligands that …
Clinical applications of antimicrobial peptides (AMPs): where do we stand now?
In this era of multi-drug resistance (MDR), antimicrobial peptides (AMPs) are one of the most
promising classes of potential drug candidates to combat communicable as well as …
promising classes of potential drug candidates to combat communicable as well as …
[HTML][HTML] LinTT1 peptide-functionalized liposomes for targeted breast cancer therapy
Breast cancer, with around 2 million new cases in 2019, is the second most common cancer
worldwide and the second leading cause of cancer death among females. The aim of this …
worldwide and the second leading cause of cancer death among females. The aim of this …