The ability of chemical modifications of single nucleotides to alter the electrostatic charge,
hydrophobic surface and base pairing of RNA molecules is exploited for the clinical use of …

Abstract N 6-Methyladenosine (m6A), the most prevalent internal modification in eukaryotic
mRNA, has been extensively and increasingly studied over the past decade. Dysregulation …

Over decades, researchers have focused on the epigenetic control of DNA-templated
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …

Cuproptosis, caused by excessively high copper concentrations, is urgently exploited as a
potential cancer therapeutic. However, the mechanisms underlying the initiation …

RNA modification is a dynamic and reversible process regulated by a series of writers,
erasers and readers (WERs). Abnormal changes of WERs will disrupt the RNA modification …

RNA modification has recently become a significant process of gene regulation, and the
methyltransferase-like (METTL) family of proteins plays a critical role in RNA modification …

Tumor-initiating cells (TICs) reprogram their metabolic features to meet their bioenergetic,
biosynthetic, and redox demands. Our previous study established a role for wild-type …

As an epitranscriptomic modulation manner, N6‐methyladenosine (m6A) modification plays
important roles in various diseases, including hepatocellular carcinoma (HCC). m6A …

Neutrophil extracellular traps (NETs), released by polymorphonuclear neutrophils (PMNs),
exert a robust antimicrobial function in infectious diseases such as sepsis. NETs also …

RNA N6‐methyladenosine modification is the most prevalent internal modification of
eukaryotic RNAs and has emerged as a novel field of RNA epigenetics, garnering increased …