Learning Objectives Contrast the current strengths and limitations of the three main slide-
based techniques (IHC, FISH, and CISH) currently in clinical use for testing breast cancer …

American Society of Clinical Oncology 2007 Update of Recommendations for the Use of
Tumor Markers in Breast Cancer Page 1 American Society of Clinical Oncology 2007 Update …

Abstract Learning Objectives After completing this course, the reader will be able to: Define
the historical background and biological basis of the discovery of the HER-2/neu gene and …

The HER-2/neu oncogene, a member of the epidermal growth factor receptor or erb gene
family, encodes a transmembrane tyrosine kinase receptor that has been linked to prognosis …

Medicinal mushrooms have attracted much attention recently owing to their potent
therapeutic activity, especially as chemopreventive and immunomodulatory agents. Antrodia …

Purpose: Trastuzumab-based therapy improves survival for women with human epidermal
growth factor receptor 2 (HER2)–positive advanced breast cancer. We conducted a …

Conclusion: Preoperative trastuzumab and paclitaxel is active against HER2 overexpressing
early-stage breast cancer and may be feasible as part of a sequential treatment program …

Abstract Background: The HER-2/neu oncogene and its p185 receptor protein are indicators
of a more aggressive form of breast cancer. HER-2/neu status guides Herceptin therapy …

Monoclonal antibodies (mAbs) have been developed as therapeutics, especially for the
treatment of cancer, inflammation, and infectious diseases. Because the glycosylation of …

The first part of this two-part review of established and emerging breast cancer biomarkers
and molecular diagnostics considers breast cancer predisposition, screening tests for …