RBM3 is an outstanding cold shock protein with multiple physiological functions beyond hypothermia

Y Hu, Y Liu, X Quan, W Fan, B Xu… - Journal of Cellular …, 2022 - Wiley Online Library
RNA‐binding motif protein 3 (RBM3), an outstanding cold shock protein, is rapidly
upregulated to ensure homeostasis and survival in a cold environment, which is an …

Massage as a mechanotherapy for skeletal muscle

DW Van Pelt, MM Lawrence, BF Miller… - Exercise and sport …, 2021 - journals.lww.com
Massage is anecdotally associated with many health benefits, but physiological and
clinically relevant mechanisms recently have begun to be investigated in a controlled …

Anti-inflammatory therapy enables robot-actuated regeneration of aged muscle

SL McNamara, BR Seo, BR Freedman, EB Roloson… - Science robotics, 2023 - science.org
Robot-actuated mechanical loading (ML)–based therapies (“mechanotherapies”) can
promote regeneration after severe skeletal muscle injury, but the effectiveness of such …

[HTML][HTML] Manual therapy regulates oxidative stress in aging rat lumbar intervertebral discs through the SIRT1/FOXO1 pathway

C Yao, G Guo, R Huang, C Tang, Q Zhu… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
With the increasing burden of a globally aging population, low back pain has become one of
the most common musculoskeletal disorders, caused mainly by intervertebral disc (IVD) …

Massage as a mechanotherapy promotes skeletal muscle protein and ribosomal turnover but does not mitigate muscle atrophy during disuse in adult rats

MM Lawrence, DW Van Pelt, AL Confides… - Acta …, 2020 - Wiley Online Library
Aim Interventions that decrease atrophy during disuse are desperately needed to maintain
muscle mass. We recently found that massage as a mechanotherapy can improve muscle …

Applying causal discovery to single-cell analyses using CausalCell

Y Wen, J Huang, S Guo, Y Elyahu, A Monsonego… - Elife, 2023 - elifesciences.org
Correlation between objects is prone to occur coincidentally, and exploring correlation or
association in most situations does not answer scientific questions rich in causality. Causal …

Mechanotherapy reprograms aged muscle stromal cells to remodel the extracellular matrix during recovery from disuse

ZR Hettinger, Y Wen, BD Peck, K Hamagata… - Function, 2022 - academic.oup.com
Aging is accompanied by reduced remodeling of skeletal muscle extracellular matrix (ECM),
which is exacerbated during recovery following periods of disuse atrophy. Mechanotherapy …

Age-related susceptibility to muscle damage following mechanotherapy in rats recovering from disuse atrophy

ZR Hettinger, K Hamagata, AL Confides… - The Journals of …, 2021 - academic.oup.com
The inability to fully recover lost muscle mass following periods of disuse atrophy
predisposes older adults to lost independence and poor quality of life. We have previously …

Muscle from aged rats is resistant to mechanotherapy during atrophy and reloading

MM Lawrence, DW Van Pelt, AL Confides, ZR Hettinger… - Geroscience, 2021 - Springer
Massage is a viable mechanotherapy to improve protein turnover during disuse atrophy and
improve muscle regrowth during recovery from disuse atrophy in adult muscle. Therefore …

Temporal disruption of neuromuscular communication and muscle atrophy following noninvasive ACL injury in rats

ER Hunt, SM Davi, CN Parise, K Clark… - Journal of Applied …, 2022 - journals.physiology.org
Many patients with anterior cruciate ligament (ACL) injuries have persistent quadriceps
muscle atrophy, even after considerable time in rehabilitation. Understanding the factors that …