[HTML][HTML] Polysaccharide peptide conjugates: chemistry, properties and applications

T Mohan, KS Kleinschek, R Kargl - Carbohydrate Polymers, 2022 - Elsevier
The intention of this publication is to give an overview on research related to conjugates of
polysaccharides and peptides. Dextran, chitosan, and alginate were selected, to cover four …

Nanocarriers for nuclear imaging and radiotherapy of cancer

A Mitra, A Nan, BR Line… - Current pharmaceutical …, 2006 - ingentaconnect.com
Several nanoscale carriers (nanoparticles, liposomes, water-soluble polymers, micelles and
dendrimers) have been developed for targeted delivery of cancer diagnostic and therapeutic …

Selection and characterization of HER2/neu-binding affibody ligands

M Wikman, AC Steffen, E Gunneriusson… - Protein Engineering …, 2004 - academic.oup.com
Affibody®(affibody) ligands that are specific for the extracellular domain of human epidermal
growth factor receptor 2 (HER2/neu) have been selected by phage display technology from …

Recent trends in the use of polysaccharides for improved delivery of therapeutic agents: pharmacokinetic and pharmacodynamic perspectives

R Mehvar - Current pharmaceutical biotechnology, 2003 - ingentaconnect.com
New and innovative methods of delivery of therapeutic agents using polysaccharides have
been recently developed, which target site of action, increase the intensity and/or prolong …

Radiolabelled polymeric materials for imaging and treatment of cancer: quo vadis?

K Pant, O Sedláček, RA Nadar… - Advanced healthcare …, 2017 - Wiley Online Library
Owing to their tunable blood circulation time and suitable plasma stability, polymer‐based
nanomaterials hold a great potential for designing and utilising multifunctional nanocarriers …

Influence of labelling methods on biodistribution and imaging properties of radiolabelled peptides for visualisation of molecular therapeutic targets

V Tolmachev, A Orlova - Current medicinal chemistry, 2010 - ingentaconnect.com
Progress in genomics and proteomics provides clinical oncology with new anti-cancer
drugs, which target selectively aberrantly expressed membrane proteins and associated …

Cellular studies of binding, internalization and retention of a radiolabeled EGFR-binding affibody molecule

E Nordberg, M Friedman, L Göstring, GP Adams… - Nuclear medicine and …, 2007 - Elsevier
INTRODUCTION: The cellular binding and processing of an epidermal growth factor
receptor (EGFR) targeting affibody molecule,(ZEGFR: 955) 2, was studied. This new and …

Evaluation of radiolabeled ML04, a putative irreversible inhibitor of epidermal growth factor receptor, as a bioprobe for PET imaging of EGFR-overexpressing tumors

G Abourbeh, S Dissoki, O Jacobson, A Litchi… - Nuclear medicine and …, 2007 - Elsevier
Overexpression of epidermal growth factor receptor (EGFR) has been implicated in tumor
development and malignancy. Evaluating the degree of EGFR expression in tumors could …

Polysaccharides as carriers of bioactive agents for medical applications

R Pawar, W Jadhav, S Bhusare, R Borade… - Natural-based polymers …, 2008 - Elsevier
Publisher Summary Polysaccharides are made either of one type of small unit, or with two
alternating units that are not only informational molecules such as protein and nucleic acids …

Affibody-mediated tumour targeting of HER-2 expressing xenografts in mice

AC Steffen, A Orlova, M Wikman, FY Nilsson… - European journal of …, 2006 - Springer
Purpose Targeted delivery of radionuclides for diagnostic and therapeutic applications has
until recently largely been limited to receptor ligands, antibodies and antibody-derived …