Protein subcellular localization is tightly controlled and intimately linked to protein function in
health and disease. Capturing the spatial proteome—that is, the localizations of proteins and …

The eukaryotic cell is compartmentalized into subcellular niches, including membrane-
bound and membrane-less organelles. Proteins localize to these niches to fulfil their …

Spatial proteomics is an interdisciplinary field that investigates the localization and dynamics
of proteins, and it has gained extensive attention in recent years, especially the subcellular …

Cellular microscopy images contain rich insights about biology. To extract this information,
researchers use features, or measurements of the patterns of interest in the images. Here …

The spatial distribution of proteome at subcellular levels provides clues for protein functions,
thus is important to human biology and medicine. Imaging-based methods are one of the …

Protein subcellular localization is an essential and highly regulated determinant of protein
function. Major advances in mass spectrometry and imaging have allowed the development …

Single-cell image analysis provides a powerful approach for studying cell-to-cell
heterogeneity, which is an important attribute of isogenic cell populations, from microbial …

The ability to measure the abundance and visualize the localization of proteins across the
yeast proteome has stimulated hypotheses on gene function and fueled discoveries. While …

Protein subcellular locations are closely related to the function of proteins. By detecting the
abnormalities in subcellular locations, we can infer the occurrence of some diseases and …

The mammalian cell is a complex entity, with membrane-bound and membrane-less
organelles playing vital roles in regulating cellular homeostasis. Organellar protein niches …