Epigallocatechin-3-Gallate (EGCG): New therapeutic perspectives for neuroprotection, aging, and neuroinflammation for the modern age

A Payne, S Nahashon, E Taka, GM Adinew… - Biomolecules, 2022 - mdpi.com
Alzheimer's and Parkinson's diseases are the two most common forms of neurodegenerative
diseases. The exact etiology of these disorders is not well known; however, environmental …

New era of artificial intelligence and machine learning-based detection, diagnosis, and therapeutics in Parkinson's disease

R Gupta, S Kumari, A Senapati, RK Ambasta… - Ageing research …, 2023 - Elsevier
Parkinson's disease (PD) is characterized by the loss of neuronal cells, which leads to
synaptic dysfunction and cognitive defects. Despite the advancements in treatment …

Neuroprotective effects and therapeutic potential of the citrus flavonoid hesperetin in neurodegenerative diseases

JA Evans, P Mendonca, KFA Soliman - Nutrients, 2022 - mdpi.com
Neurodegenerative disorders affect more than fifty million Americans each year and
represent serious health threats as the population ages. Neuroinflammation and oxidative …

[HTML][HTML] IgG glycans in health and disease: Prediction, intervention, prognosis, and therapy

S Shkunnikova, A Mijakovac, L Sironic, M Hanic… - Biotechnology …, 2023 - Elsevier
Immunoglobulin (IgG) glycosylation is a complex enzymatically controlled process, essential
for the structure and function of IgG. IgG glycome is relatively stable in the state of …

Inflammation: A new look at an old problem

E Gusev, Y Zhuravleva - International Journal of Molecular Sciences, 2022 - mdpi.com
Pro-inflammatory stress is inherent in any cells that are subject to damage or threat of
damage. It is defined by a number of universal components, including oxidative stress …

[HTML][HTML] Aging Process and Related Diseases

F Taheri, E Rahmani, SS Fard, M Rezaei, A Ayati… - Kindle, 2023 - preferpub.org
The aging process is a complex biological phenomenon that results in the gradual decline of
physiological function and an increased risk of age-related diseases. While aging is a …

Alzheimer's disease—Biochemical and psychological background for diagnosis and treatment

BK Beata, J Wojciech, K Johannes, L Piotr… - International journal of …, 2023 - mdpi.com
There is a paucity of empirical research on the use of non-pharmacological interventions to
both treat and curb the spread of Alzheimer's disease (AD) across the globe. This paper …

Sex and gender differences in Alzheimer's disease, Parkinson's disease, and Amyotrophic Lateral Sclerosis: A narrative review

A Nicoletti, R Baschi, CE Cicero, S Iacono… - Mechanisms of ageing …, 2023 - Elsevier
ABSTRACT Neurodegenerative diseases (NDs), including Alzheimer's disease (AD),
Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), exhibit high phenotypic …

Mitochondrial function and dynamics in neural stem cells and neurogenesis: Implications for neurodegenerative diseases

P Coelho, L Fão, S Mota, AC Rego - Ageing Research Reviews, 2022 - Elsevier
Mitochondria have been largely described as the powerhouse of the cell and recent findings
demonstrate that this organelle is fundamental for neurogenesis. The mechanisms …

CNS Ageing in health and neurodegenerative disorders

E Kesidou, P Theotokis, O Damianidou… - Journal of Clinical …, 2023 - mdpi.com
The process of ageing is characteristic of multicellular organisms associated with late stages
of the lifecycle and is manifested through a plethora of phenotypes. Its underlying …