First multicentre report of in vitro resistance rates in candidaemia isolates in Turkey

S Arikan-Akdagli, D Gülmez, Ö Doğan… - Journal of global …, 2019 - Elsevier
Objectives This study investigated the antifungal resistance rates of isolates from
candidaemia patients in 12 tertiary-care centres in Turkey. Methods A total of 1991 Candida …

Set of Classical PCRs for Detection of Mutations in Candida glabrata FKS Genes Linked with Echinocandin Resistance

C Dudiuk, S Gamarra, F Leonardeli… - Journal of clinical …, 2014 - Am Soc Microbiol
Clinical echinocandin resistance among Candida glabrata strains is increasing, especially
in the United States. Antifungal susceptibility testing is considered mandatory to guide …

Strategies of targeting CYP51 for IFIs therapy: Emerging prospects, opportunities and challenges

R Zhang, Y Wang, A Wu, J Wang, J Zhang - European Journal of Medicinal …, 2023 - Elsevier
CYP51, a monooxygenase associated with the sterol synthesis pathway, is responsible for
the catalysis of the 14-methyl hydroxylation reaction of lanosterol precursors. This enzyme is …

The A395T Mutation in ERG11 Gene Confers Fluconazole Resistance in Candida tropicalis Causing Candidemia

J Tan, J Zhang, W Chen, Y Sun, Z Wan, R Li, W Liu - Mycopathologia, 2015 - Springer
The mechanism of fluconazole resistance in Candida tropicalis is still unclear. Recently, we
isolated a fluconazole-resistant strain of C. tropicalis from the blood specimen of a patient …

[HTML][HTML] Clinical and molecular characteristics of bloodstream infections caused by Candida albicans in children from 2003 to 2011

MH Tsai, SH Wang, JF Hsu, LC Lin, SM Chu… - Clinical Microbiology …, 2015 - Elsevier
We investigated the clinical and molecular characteristics of Candida albicans bloodstream
infection (BSI) in children from a tertiary-level medical centre in Taiwan over a 9-year period …

Antifungal susceptibilities of Candida isolates causing bloodstream infections at a medical center in Taiwan, 2009-2010

YT Huang, CY Liu, CH Liao, KP Chung… - Antimicrobial agents …, 2014 - Am Soc Microbiol
ABSTRACT We used the Sensititre YeastOne (SYO) method (Trek Diagnostic Systems) to
determine the MICs of nine antifungal agents against 474 nonduplicate blood Candida …

Catheter-related Candidabloodstream infection in intensive care unit patients: a subgroup analysis of the China-SCAN study

B Hu, Z Du, Y Kang, B Zang, W Cui, B Qin… - BMC infectious …, 2014 - Springer
Background In patients hospitalized in intensive care units (ICU), Candida infections are
associated with increased morbidity, mortality and costs. However, previous studies reported …

[HTML][HTML] Caspofungin pharmacokinetics and probability of target attainment in ICU patients in China

F Li, M Zhou, Z Jiao, Z Zou, E Yu, Z He - Journal of Global Antimicrobial …, 2021 - Elsevier
Objectives Effective antifungal therapy is important to reduce mortality in patients with
invasive fungal infections (IFIs). Numerous factors affect pharmacokinetic/pharmacodynamic …

Epidemiology and antifungal susceptibilities of yeast isolates causing invasive infections across urban Beijing, China

LN Guo, M Xiao, B Cao, F Qu, YL Zhan, YJ Hu… - Future …, 2017 - Taylor & Francis
Aim: To investigate the species distribution and antifungal susceptibility profiles of yeast
isolates causing invasive infections across Beijing. Materials & methods: A total of 1201 …

A ten-year retrospective study of invasive candidiasis in a tertiary hospital in Beijing

ZH Yang, YG Song, RY Li - Biomedical and Environmental Sciences, 2021 - Elsevier
Objective This study aimed to evaluate the epidemiological, clinical and mycological
characteristics of invasive candidiasis (IC) in China. Methods A ten-year retrospective study …