New perspectives on the origins and heterogeneity of mast cells

AL St. John, APS Rathore, F Ginhoux - Nature Reviews Immunology, 2023 - nature.com
Mast cells are immune cells of the haematopoietic lineage that are now thought to have
multifaceted functions during homeostasis and in various disease states. Furthermore, while …

[HTML][HTML] The immunomodulatory mechanisms for acupuncture practice

M Wang, W Liu, J Ge, S Liu - Frontiers in immunology, 2023 - frontiersin.org
The system physiology approaches that emerge in western countries in recent years echo
the holistic view of ancient Traditional Chinese Medicine (TCM) practices that deal with the …

A common framework of monocyte-derived macrophage activation

DE Sanin, Y Ge, E Marinkovic, AM Kabat… - Science …, 2022 - science.org
Macrophages populate every organ during homeostasis and disease, displaying features of
tissue imprinting and heterogeneous activation. The disconnected picture of macrophage …

[PDF][PDF] Neutralizing IL-8 potentiates immune checkpoint blockade efficacy for glioma

H Liu, Q Zhao, L Tan, X Wu, R Huang, Y Zuo, L Chen… - Cancer Cell, 2023 - cell.com
Malignant gliomas are largely refractory to immune checkpoint blockade (ICB) therapy. To
explore the underlying immune regulators, we examine the microenvironment in glioma and …

[HTML][HTML] Mast cell and eosinophil activation are associated with COVID-19 and TLR-mediated viral inflammation: implications for an anti-Siglec-8 antibody

S Gebremeskel, J Schanin, KM Coyle… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection represents a
global health crisis. Immune cell activation via pattern recognition receptors has been …

[HTML][HTML] Gingiva-derived mesenchymal stem cells: potential application in tissue engineering and regenerative medicine-a comprehensive review

D Kim, AE Lee, Q Xu, Q Zhang, AD Le - Frontiers in Immunology, 2021 - frontiersin.org
A unique subpopulation of mesenchymal stem cells (MSCs) has been isolated and
characterized from human gingival tissues (GMSCs). Similar to MSCs derived from other …

[HTML][HTML] Landscape of mast cell populations across organs in mice and humans

M Tauber, L Basso, J Martin, L Bostan… - Journal of Experimental …, 2023 - rupress.org
Mast cells (MCs) are tissue-resident immune cells that exhibit homeostatic and neuron-
associated functions. Here, we combined whole-tissue imaging and single-cell RNA …

Multifaceted MRGPRX2: New insight into the role of mast cells in health and disease

S Roy, CCN Ayudhya, M Thapaliya, V Deepak… - Journal of Allergy and …, 2021 - Elsevier
Cutaneous mast cells (MCs) express Mas-related G protein–coupled receptor-X2
(MRGPRX2; mouse ortholog MrgprB2), which is activated by an ever-increasing number of …

[HTML][HTML] The chicken embryo model: a novel and relevant model for immune-based studies

P Garcia, Y Wang, J Viallet… - Frontiers in immunology, 2021 - frontiersin.org
Dysregulation of the immune system is associated with many pathologies, including
cardiovascular diseases, diabetes, and cancer. To date, the most commonly used models in …

The ingenious mast cell: Contemporary insights into mast cell behavior and function

JS Dahlin, M Maurer, DD Metcalfe, G Pejler… - Allergy, 2022 - Wiley Online Library
Mast cells are (in) famous for their role in allergic diseases, but the physiological and
pathophysiological roles of this ingenious cell are still not fully understood. Mast cells are …