The discovery and development of rivaroxaban, an oral, direct factor Xa inhibitor

E Perzborn, S Roehrig, A Straub, D Kubitza… - Nature Reviews Drug …, 2011 - nature.com
The activated serine protease factor Xa is a promising target for new anticoagulants. After
studies on naturally occurring factor Xa inhibitors indicated that such agents could be …

Fast-track surgery—an update on physiological care principles to enhance recovery

H Kehlet - Langenbeck's archives of surgery, 2011 - Springer
Introduction The concept of fast-track surgery (enhanced recovery programs) has been
evolved and been documented to be successful by decreasing length of stay, morbidity and …

Antithrombotic therapy and body mass: an expert position paper of the ESC Working Group on Thrombosis

B Rocca, KAA Fox, RA Ajjan, F Andreotti… - European heart …, 2018 - academic.oup.com
The success of trials that have shown net clinical benefits of antithrombotic drugs as well as
the increasing prevalence of cardiovascular diseases in an ageing population have led to …

Venous thromboembolism prophylaxis using the Caprini score

I Golemi, JPS Adum, A Tafur, J Caprini - Disease-a-Month, 2019 - Elsevier
Venous thromboembolism (VTE) including pulmonary embolism (PE) and deep vein
thrombosis (DVT) is one of the leading causes of preventable cardiovascular disease in the …

Rivaroxaban for the prevention of venous thromboembolism after hip or knee arthroplasty

AGG Turpie, MR Lassen, BI Eriksson… - Thrombosis and …, 2011 - thieme-connect.com
Four phase III studies compared oral rivaroxaban with subcutaneous enoxaparin for the
prevention of venous thromboembolism (VTE) after total hip or knee arthroplasty (THA or …

Thromboprophylaxis for trauma patients

LM Barrera, P Perel, K Ker, R Cirocchi… - Cochrane Database …, 2013 - cochranelibrary.com
Background Trauma is a leading causes of death and disability in young people. Venous
thromboembolism (VTE) is a principal cause of death. Trauma patients are at high risk of …

Neuraxial blockade for the prevention of postoperative mortality and major morbidity: an overview of Cochrane systematic reviews

J Guay, P Choi, S Suresh, N Albert… - Cochrane Database …, 2014 - cochranelibrary.com
Background Various beneficial effects derived from neuraxial blocks have been reported.
However, it is unclear whether these effects have an influence on perioperative mortality and …

Indications, complications, and management of inferior vena cava filters: the experience in 952 patients at an academic hospital with a level I trauma center

S Sarosiek, M Crowther, JM Sloan - JAMA internal medicine, 2013 - jamanetwork.com
Importance Retrievable inferior vena cava (IVC) filters were designed to provide temporary
protection from pulmonary embolism, sparing patients from long-term complications of …

[HTML][HTML] Racial differences in venous thromboembolism

NA Zakai, LA McClure - Journal of Thrombosis and Haemostasis, 2011 - Elsevier
The incidence of venous thrombosis (VTE) varies by race, with African‐Americans having
over 5‐fold greater incidence than Asian‐ancestry populations, and an intermediate risk for …

[HTML][HTML] A prospective open-label study of endovascular treatment of chronic cerebrospinal venous insufficiency

P Zamboni, R Galeotti, E Menegatti… - Journal of vascular …, 2009 - Elsevier
OBJECTIVE: Chronic cerebrospinal venous insufficiency (CCSVI) is characterized by
combined stenoses of the principal pathways of extracranial venous drainage, including the …