It is now generally accepted that macromolecules do not act in isolation but “live” in a
crowded environment, that is, an environment populated by numerous different molecules …

Liquid–liquid phase separation (LLPS) is an emerging phenomenon in cell physiology and
diseases. The weak multivalent interaction prerequisite for LLPS is believed to be facilitated …

Compartmentalization is an essential feature of eukaryotic life and is achieved both via
membrane-bound organelles, such as mitochondria, and membrane-less biomolecular …

Cold induction of nuclear FRIGIDA condensation in Arabidopsis | Nature Skip to main content
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In biological systems, liquid and solid-like biomolecular condensates may contain the same
molecules but their behaviour, including movement, elasticity, and viscosity, is different on …

We introduce MolPhase, an advanced algorithm for predicting protein phase separation
(PS) behavior that improves accuracy and reliability by utilizing diverse physicochemical …

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Whether phase-separation is involved in the organization of the transcriptional machinery
and if it aids or inhibits the transcriptional process is a matter of intense debate. In this Mini …

Biomolecular condensates play important roles in a wide array of fundamental biological
processes, such as cellular compartmentalization, cellular regulation, and other biochemical …

Nuclear compartments form via biomolecular phase separation, mediated through
multivalent properties of biomolecules concentrated within condensates. Certain …