[HTML][HTML] The microbiota of the respiratory tract: gatekeeper to respiratory health

WH Man, WAA de Steenhuijsen Piters… - Nature Reviews …, 2017 - nature.com
The respiratory tract is a complex organ system that is responsible for the exchange of
oxygen and carbon dioxide. The human respiratory tract spans from the nostrils to the lung …

The role of the local microbial ecosystem in respiratory health and disease

WAA de Steenhuijsen Piters… - … Transactions of the …, 2015 - royalsocietypublishing.org
Respiratory tract infections are a major global health concern, accounting for high morbidity
and mortality, especially in young children and elderly individuals. Traditionally, highly …

Group B streptococcal maternal colonization and neonatal disease: molecular mechanisms and preventative approaches

KA Patras, V Nizet - Frontiers in pediatrics, 2018 - frontiersin.org
Group B Streptococcus (GBS) colonizes the gastrointestinal and vaginal epithelium of a
significant percentage of healthy women, with potential for ascending intrauterine infection …

Group B Streptococcus adaptation promotes survival in a hyperinflammatory diabetic wound environment

RA Keogh, AL Haeberle, CJ Langouët-Astrié… - Science …, 2022 - science.org
Diabetic wounds have poor healing outcomes due to the presence of numerous pathogens
and a dysregulated immune response. Group B Streptococcus (GBS) is commonly isolated …

Mechanisms of synergy in polymicrobial infections

JL Murray, JL Connell, A Stacy, KH Turner… - Journal of …, 2014 - Springer
Communities of microbes can live almost anywhere and contain many different species.
Interactions between members of these communities often determine the state of the habitat …

Peptide pheromone signaling in Streptococcus and Enterococcus

LC Cook, MJ Federle - FEMS microbiology reviews, 2014 - academic.oup.com
Intercellular chemical signaling in bacteria, commonly referred to as quorum sensing (QS),
relies on the production and detection of compounds known as pheromones to elicit …

Streptococcus pyogenes adhesion and colonization

S Brouwer, TC Barnett, T Rivera‐Hernandez… - FEBS …, 2016 - Wiley Online Library
Streptococcus pyogenes (group A Streptococcus, GAS) is a human‐adapted pathogen
responsible for a wide spectrum of disease. GAS can cause relatively mild illnesses, such as …

Genetic and structural analyses of RRNPP intercellular peptide signaling of Gram-positive bacteria

MB Neiditch, GC Capodagli, G Prehna… - Annual review of …, 2017 - annualreviews.org
Bacteria use diffusible chemical messengers, termed pheromones, to coordinate gene
expression and behavior among cells in a community by a process known as quorum …

Quorum sensing in group A Streptococcus

JC Jimenez, MJ Federle - Frontiers in cellular and infection …, 2014 - frontiersin.org
Quorum sensing (QS) is a widespread phenomenon in the microbial world that has
important implications in the coordination of population-wide responses in several bacterial …

Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model

RV Wilkening, C Langouët-Astrié, MM Severn… - Cell reports, 2023 - cell.com
Streptococcus pyogenes is an obligate human pathobiont associated with many disease
states. Here, we present a model of S. pyogenes infection using intact murine epithelium …