[HTML][HTML] Multiple length peptide-pheromone variants produced by Streptococcus pyogenes directly bind Rgg proteins to confer transcriptional regulation

C Aggarwal, JC Jimenez, D Nanavati… - Journal of Biological …, 2014 - ASBMB
Streptococcus pyogenes, a human-restricted pathogen, accounts for substantial mortality
related to infections worldwide. Recent studies indicate that streptococci produce and …

[HTML][HTML] Microbial co-culture: harnessing intermicrobial signaling for the production of novel antimicrobials

SC Moody - Future Microbiology, 2014 - Taylor & Francis
Bacteria and fungi are masters of communication. They engage in constant information
transfer with their neighbors, competitors and hosts. This elaborate 'social networking'is …

A novel streptococcal cell–cell communication peptide promotes pneumococcal virulence and biofilm formation

RA Cuevas, R Eutsey, A Kadam… - Molecular …, 2017 - Wiley Online Library
Streptococcus pneumoniae (pneumococcus) is a major human pathogen. It is a common
colonizer of the human respiratory track, where it utilizes cell–cell communication systems to …

[HTML][HTML] Streptococcal peptides and their roles in host-microbe interactions

ER Wahlenmayer, DE Hammers - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
The genus Streptococcus encompasses many bacterial species that are associated with
hosts, ranging from asymptomatic colonizers and commensals to pathogens with a …

Induction of a quorum sensing pathway by environmental signals enhances group A streptococcal resistance to lysozyme

JC Chang, JC Jimenez, MJ Federle - Molecular microbiology, 2015 - Wiley Online Library
The human‐restricted pathogen S treptococcus pyogenes (G roup AS treptococcus, GAS) is
responsible for wide‐ranging pathologies at numerous sites in the body but has the …

The Rgg1518 transcriptional regulator is a necessary facet of sugar metabolism and virulence in Streptococcus pneumoniae

B Shlla, O Gazioglu, S Shafeeq, I Manzoor… - Molecular …, 2021 - Wiley Online Library
Rggs are a group of transcriptional regulators with diverse roles in metabolism and
virulence. Here, we present work on the Rgg1518/SHP1518 quorum sensing system of …

Characterization of a signaling system in Streptococcus mitis that mediates interspecies communication with Streptococcus pneumoniae

R Junges, K Sturød, G Salvadori… - Applied and …, 2019 - Am Soc Microbiol
Streptococcus mitis is found in the oral cavity and nasopharynx and forms a significant
portion of the human microbiome. In this study, in silico analyses indicated the presence of …

[HTML][HTML] Daily HIV pre-exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate-emtricitabine reduced Streptococcus and increased Erysipelotrichaceae in …

MP Dubé, SY Park, H Ross, TMT Love, SR Morris… - Scientific reports, 2018 - nature.com
Daily PrEP is highly effective at preventing HIV-1 acquisition, but risks of long-term tenofovir
disoproxil fumarate plus emtricitabine (TDF-FTC) include renal decline and bone mineral …

Current understanding of Group A Streptococcal biofilms

HKN Vyas, EJ Proctor, J McArthur… - Current Drug …, 2019 - ingentaconnect.com
Background: It has been proposed that GAS may form biofilms. Biofilms are microbial
communities that aggregate on a surface, and exist within a self-produced matrix of …

Current views of haemolytic streptococcal pathogenesis

LKK Tan, LRJ Eccersley… - Current Opinion in …, 2014 - journals.lww.com
Molecular biology has enhanced our understanding of the intricate balance of host–
pathogen interactions that result in clearance or establishment of invasive streptococcal …