[HTML][HTML] Glycogen synthase kinase-3 signaling in Alzheimer's disease
E Lauretti, O Dincer, D Praticò - … et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
Alzheimer's disease (AD) is the most common form of neurodegenerative disorder with
dementia, accounting for approximately 70% of the all cases. Currently, 5.8 million people in …
dementia, accounting for approximately 70% of the all cases. Currently, 5.8 million people in …
[HTML][HTML] Glucagon-like peptide-1 (GLP-1) receptor agonists and neuroinflammation: Implications for neurodegenerative disease treatment
Chronic, excessive neuroinflammation is a key feature of neurodegenerative diseases such
as Alzheimer's disease (AD) and Parkinson's disease (PD). However, neuroinflammatory …
as Alzheimer's disease (AD) and Parkinson's disease (PD). However, neuroinflammatory …
The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease
A Webers, MT Heneka… - Immunology and cell …, 2020 - Wiley Online Library
Alzheimer's disease (AD) is characterized by amyloid beta (Aβ) accumulation, tau pathology
and neuroinflammation. Recently, there has been considerable interest in the role of …
and neuroinflammation. Recently, there has been considerable interest in the role of …
[HTML][HTML] Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration
Synaptic loss and neuron death are the underlying cause of neurodegenerative diseases
such as Alzheimer's disease (AD); however, the modalities of cell death in those diseases …
such as Alzheimer's disease (AD); however, the modalities of cell death in those diseases …
[HTML][HTML] Hyperactivation of P2X7 receptors as a culprit of COVID-19 neuropathology
DE Ribeiro, A Oliveira-Giacomelli, T Glaser… - Molecular …, 2021 - nature.com
Scientists and health professionals are exhaustively trying to contain the coronavirus
disease 2019 (COVID-19) pandemic by elucidating viral invasion mechanisms, possible …
disease 2019 (COVID-19) pandemic by elucidating viral invasion mechanisms, possible …
Role of chronic neuroinflammation in neuroplasticity and cognitive function: A hypothesis
Objective Evaluating the efficacy of 3, 6'‐dithioPomalidomide in 5xFAD Alzheimer's disease
(AD) mice to test the hypothesis that neuroinflammation is directly involved in the …
(AD) mice to test the hypothesis that neuroinflammation is directly involved in the …
NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes
Inflammation in the brain accompanies several high-impact neurological diseases including
multiple sclerosis (MS), stroke, and Alzheimer's disease. Neuroinflammation is sterile, as …
multiple sclerosis (MS), stroke, and Alzheimer's disease. Neuroinflammation is sterile, as …
[HTML][HTML] Advanced glycation end-products produced systemically and by macrophages: A common contributor to inflammation and degenerative diseases
Advanced glycation end products (AGEs) and their receptor have been implicated in the
progressions of many intractable diseases, such as diabetes and atherosclerosis, and are …
progressions of many intractable diseases, such as diabetes and atherosclerosis, and are …
[HTML][HTML] Impact of HMGB1, RAGE, and TLR4 in Alzheimer's disease (AD): from risk factors to therapeutic targeting
Alzheimer's disease (AD) is a devastating neurodegenerative disorder and a leading cause
of dementia, with accumulation of amyloid-beta (Aβ) and neurofibrillary tangles (NFTs) as …
of dementia, with accumulation of amyloid-beta (Aβ) and neurofibrillary tangles (NFTs) as …
[HTML][HTML] CB2 receptor in microglia: the guardian of self-control
JA Komorowska-Müller, AC Schmöle - International journal of molecular …, 2020 - mdpi.com
Microglia are key to maintaining the homeostasis of the brain. These immune cells of the
brain can be our biggest ally in fighting infections, but can worsen pathology or hinder …
brain can be our biggest ally in fighting infections, but can worsen pathology or hinder …