Central nervous system myelination requires recognition and signalling processes between
neuronal axons and oligodendrocytes. Complex cellular rearrangements occur in …

Central nervous system myelination requires the synthesis of large amounts of myelin basic
protein (MBP) at the axon–glia contact site. MBP messenger RNA (mRNA) is transported in …

Flavonoids constitute the largest class of dietary phytochemicals, adding essential health
value to our diet, and are emerging as key nutraceuticals. Cellular targets for dietary …

In oligodendrocytes and neurons genetic information is transmitted from the nucleus to
dendrites in the form of RNA granules. Here we describe how transport of multiple different …

In neurons, many different RNAs are targeted to dendrites where local expression of the
encoded proteins mediates synaptic plasticity during learning and memory. It is not known …

Heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNP A2/B1) has been identified as a
nuclear DNA sensor. Upon viral infection, hnRNP A2/B1 recognizes pathogen-derived DNA …

Mitochondrial dysfunction and altered transmembrane potential initiate a mitochondrial
respiratory stress response, also known as mitochondrial retrograde response, in a wide …

The gaseous neurotransmitter nitric oxide (NO), synthesized by the enzyme neuronal nitric
oxide synthase (nNOS), is thought to play a major role in the modulation of memory. We …

In neurons, translation of a message RNA can occur metres away from its transcriptional
origin and in normal cells this is orchestrated with perfection. The life of an mRNA will see it …

RNA granules are ensembles of specific RNA and protein molecules that mediate localized
translation in eukaryotic cells. The mechanisms for formation and selectivity of RNA granules …