[HTML][HTML] ABCB1 gene variants as risk factors and modulators of age of onset of demyelinating disease in Mexican patients

JLG Camacho, TC Vázquez, JJF Rivera… - Neurología (English …, 2023 - Elsevier
Introducción Las variantes C1236T, G2677T/A y C3435T del gen ABCB1 alteran la función
de la Glicoproteína P y el transporte de sustancias endógenas y exógenas en la barrera …

[HTML][HTML] Pharmacogenetics and Pharmacogenomics Impact on Aspirin Response

MA Siddiqui, C Jain, A Usmani, A Hafeez, M Khalid… - 2024 - intechopen.com
Aspirin, or Acetylsalicylic acid (ASA), is renowned for its pain-relieving and anti-inflammatory
properties. Recent insights have illuminated its mechanisms and potential applications …

Allele-specific polymerase chain reaction for the detection of single nucleotide polymorphism in amlodipine-induced gingival enlargement.

N Kala, S Babu, J Manjeu… - Journal of Clinical …, 2018 - search.ebscohost.com
What is known and objective Studies indicate that there is an increased serum concentration
of amlodipine (a calcium channel blocker used to treat hypertension and angina) in patients …

ABCG2 Single Nucleotide Polymorphism Affects Imatinib Pharmacokinetics in Lower Alpha-1-Acid Glycoprotein Levels in Humans

JW Park, H Chung, KA Kim, JM Kim, IH Park… - Frontiers in …, 2021 - frontiersin.org
Imatinib is transported extracellularly by ABCB1 and ABCG2 efflux transporters and bound
to alpha-1-acid glycoprotein (AGP) in the bloodstream. However, the clinical and …

Diltiazem augments the influence of MDR1 genotype status on cyclosporine concentration in Chinese patients with renal transplantation

Y Wang, J Li, X Wang, Y Zhang, C Wang… - Acta Pharmacologica …, 2015 - nature.com
Aim: Co-administration of diltiazem can reduce the dosage of cyclosporine (CsA) in patients
with renal transplantation. In this study, we investigated how diltiazem altered the …

Перспективы использования полиморфизма C3435T гена P-гликопротеина ABCB1 в персонализированной медицине

РЕ Казаков, ВА Евтеев, ОВ Муслимова… - Ведомости Научного …, 2017 - cyberleninka.ru
В статье представлен обзор данных научной литературы, посвященной исследованию
полиморфизма C3435T гена ABCB1, кодирующего P-гликопротеин АТФ-связывающий …

PXR* 1B 基因多态性与氨氯地平稳态谷浓度和降压疗效的相关性研究

张桂香, 袁洪, 阳国平, 黄志军 - 中国临床药理学与治疗学, 2010 - manu41.magtech.com.cn
目的: 探讨PXR11193T> C, 8055 C> T 及PXR* 1B (由11193T> C 和8055 C> T 构成)
对轻中度原发性高血压患者服用氨氯地平的稳态谷浓度及其降压疗效的影响. 方法 …

Untangling Absorption Mechanisms and Variability in Bioequivalence Studies Using Population Analysis

C Ameijeiras Rodríguez, SC Henriques… - Pharmaceutical …, 2021 - Springer
Purpose Both inter-individual (IIV) and inter-occasion (IOV) variabilities are observed in
bioequivalence studies. High IOV may be a cause of problems on the demonstration of …

抗心绞痛药物的药物基因组学研究进展

张燕青, 陈锦珊 - 中国药房, 2013 - cqvip.com
目的: 为抗心绞痛药物的临床应用和个体化给药提供参考. 方法: 查阅2000 年以来的国内,
外相关文献, 对硝酸酯类药物, β 受体阻滞药, 钙拮抗药和抗血小板药物4 类常用抗心绞痛药物的 …

Персонифицированная фармакотерапия хронического гастрита

ДМ Мусаева, ГС Очилова - Фармакология разных стран, 2020 - elibrary.ru
ПЕРСОНИФИЦИРОВАННАЯ ФАРМАКОТЕРАПИЯ ХРОНИЧЕСКОГО ГАСТРИТА
КОРЗИНА ПОИСК НАВИГАТОР СЕССИЯ КОНТАКТЫ ИНФОРМАЦИЯ О ПУБЛИКАЦИИ …