The effect of drugs in the body is directly related to its therapeutic concentration, which must
be created not only in the blood, but also in the" target" cells. The MDR-1 gene (multidrug …

Peptic ulcer disease is one of the variants of the typological response of the body when
exogenous factors of the internal environment interact (type of the nervous system …

Background Amlodipine, initially approved by the FDA in 1987, remains ampere popularly
antihypertensive food belonging to aforementioned band of drugs called dihydropyridine …

Цель. Повышение эффективности и безопасности фармакотерапии артериальной
гипертензии (АГ) 1-2-й степени путем персонализации выбора режима дозирования …

Блокаторы медленных кальциевых каналов являются субстратами генетически
полиморфного транспортера гликопротеина-Р. В исследовании изучалась ассоциация …

The MDR-1 gene encodes P-glycoprotein, a vital membrane protein found in various normal
cells throughout the body. This protein plays a crucial role in actively facilitating the …

The article reviews scientific literature on C3435T polymorphism in the ABCB1 gene which
encodes P-glycoprotein (an ATP-binding cassette transporter which is responsible for …

This article presents a comprehensive examination of the influence of genetic factors on
individual drug response in pharmacotherapy, emphasizing the potential for personalized …

The article recognizes that the individualization of medicine is an innovative direction that
increases the safety and efficiency of pharmacotherapy, a modern method of modernizing …

Частота распространения коморбидной патологии у больных артериальной
гипертонией (АГ), в частности, сочетание АГ и кислотозависимых заболеваний (КЗЗ) …