A new approach to Cas9-based genome editing in Aspergillus niger that is precise, efficient and selectable

LMC Leynaud-Kieffer, SC Curran, I Kim, JK Magnuson… - PloS one, 2019 - journals.plos.org
Aspergillus niger and other filamentous fungi are widely used in industry, but efficient
genetic engineering of these hosts remains nascent. For example, while molecular genetic …

Role of enteroaggregative Escherichia coli virulence factors in uropathogenesis

EJ Boll, C Struve, N Boisen, B Olesen… - Infection and …, 2013 - Am Soc Microbiol
ABSTRACT A multiresistant clonal Escherichia coli O78: H10 strain qualifying molecularly
as enteroaggregative Escherichia coli (EAEC) was recently shown to be the cause of a …

Molecular characterization of UpaB and UpaC, two new autotransporter proteins of uropathogenic Escherichia coli CFT073

LP Allsopp, C Beloin, GC Ulett, J Valle… - Infection and …, 2012 - Am Soc Microbiol
Uropathogenic Escherichia coli (UPEC) is the primary cause of urinary tract infection (UTI) in
the developed world. The major factors associated with virulence of UPEC are fimbrial …

The Transcriptional Antiterminator RfaH Represses Biofilm Formation in Escherichia coli

C Beloin, K Michaelis, K Lindner, P Landini… - Journal of …, 2006 - Am Soc Microbiol
We investigated the influence of regulatory and pathogenicity island-associated factors
(Hha, RpoS, LuxS, EvgA, RfaH, and tRNA5Leu) on biofilm formation by uropathogenic …

Biofilms Formed by Gram-Negative Bacteria Undergo Increased Lipid A Palmitoylation, Enhancing In Vivo Survival

S Chalabaev, A Chauhan, A Novikov, P Iyer… - MBio, 2014 - Am Soc Microbiol
Bacterial biofilm communities are associated with profound physiological changes that lead
to novel properties compared to the properties of individual (planktonic) bacteria. The study …

The flagellar sigma factor FliA regulates adhesion and invasion of Crohn disease-associated Escherichia coli via a cyclic dimeric GMP-dependent pathway

L Claret, S Miquel, N Vieille, DA Ryjenkov… - Journal of biological …, 2007 - ASBMB
The invasion of intestinal epithelial cells by the Crohn disease-associated adherent-invasive
Escherichia coli (AIEC) strain LF82 depends on surface appendages, such as type 1 pili and …

Colonization and immune modulation properties of Klebsiella pneumoniae biofilm-dispersed cells

C Guilhen, S Miquel, N Charbonnel, L Joseph… - npj Biofilms and …, 2019 - nature.com
Biofilm-dispersal is a key determinant for further dissemination of biofilm-embedded
bacteria. Recent evidence indicates that biofilm-dispersed bacteria have transcriptional …

The PagN protein of Salmonella enterica serovar Typhimurium is an adhesin and invasin

MA Lambert, SGJ Smith - BMC microbiology, 2008 - Springer
Background The pagN gene of Salmonella enterica serovar Typhimurium is a PhoP-
regulated gene that is up-regulated during growth within macrophages and in vivo in murine …

Fur Activates the Expression of Salmonella enterica Pathogenicity Island 1 by Directly Interacting with the hilD Operator In Vivo and In Vitro

L Teixidó, B Carrasco, JC Alonso, J Barbé, S Campoy - PLoS One, 2011 - journals.plos.org
Previous studies have established that the expression of Salmonella enterica pathogenicity
island 1 (SPI1), which is essential for epithelial invasion, is mainly regulated by the HilD …

oxyR, a LysR-Type Regulator Involved in Klebsiella pneumoniae Mucosal and Abiotic Colonization

C Hennequin, C Forestier - Infection and immunity, 2009 - Am Soc Microbiol
Colonization of the gastrointestinal tract is the first event in Klebsiella pneumoniae
nosocomial infections, followed by colonization of the bladder or respiratory tract or entry …