Heart failure is a complex medical syndrome that is attributed to a number of risk factors;
nevertheless, its clinical presentation is quite similar among the different etiologies. Heart …

The ryanodine receptor type 2 (RyR) is a key player in Ca 2+ handling during excitation-
contraction coupling. During each heartbeat, RyR channels are responsible for linking the …

The cardiac ryanodine receptor (RyR2) is an intracellular Ca 2+ release channel vital for the
function of the heart. Physiologically, RyR2 is triggered to release Ca 2+ from the …

Cardiac arrhythmias are life-threatening events in which the heart develops an irregular
rhythm. Mishandling of Ca 2+ within the myocytes of the heart has been widely …

Diabetes mellitus (DM) and heart failure (HF) are comorbid conditions associated with
significant morbidity and mortality worldwide. Despite the availability of novel and effective …

Lutein, a plant-derived xanthophyl-carotenoid, is an exceptional antioxidant and anti-
inflammatory constituent found in food. High dietary intake of lutein is beneficial against eye …

Right ventricular dysfunction (RVD) can follow primary pulmonary diseases, but the most
common cause of its development is left-sided heart failure (HF). RVD is associated with HF …

Catecholaminergic polymorphic ventricular tachycardia (CPVT), a rare autosomal dominant
or recessive disease, usually results in syncope or sudden cardiac death. Most CPVT …

Background: Monitoring and evaluation of adverse effects of food additives as extensively
used compounds is of crucial value to lower the expected harmful effects on human health …