Gene therapy by expression constructs or down-regulation of certain genes has shown great
potential for the treatment of various diseases. The wide clinical application of nucleic acid …

Abstract Poly (amidoamine)(PAMAM) dendrimers are well-defined, highly branched
macromolecules with numerous active amine groups on the surface. Because of their …

Simple Summary Primary liver cancer, also known as Hepatocellular carcinoma (HCC), is
considered to be a major global health challenge. Due to delays in diagnosis at early …

Gene therapy is a promising strategy for treating challenging diseases. The successful
delivery of genes is a critical step for gene therapy. However, concerns about …

Paclitaxel (PTX) and docetaxel (DTX) are key members of taxanes with high anti-tumor
activity against various cancer cells. These chemotherapeutic agents suffer from a number of …

For specific targeting of cancer tissues, adequate information about the cancer tissue
environment, cancer cell pathology, and available methods and limits of such methods is …

Cancer continues to be the leading cause of death worldwide. Hepatocellular carcinoma
(HCC), a prominent form of liver cancer, is the second leading cause of cancer-related …

Hepatocellular carcinoma (HCC) is the most common primary liver cancer with high
morbidity and mortality worldwide. Chemotherapy is recommended to patients with …

Malignancies of hepatocellular carcinoma (HCC) are rapidly spreading and commonly fatal.
Like most cancers, the gene expression patterns in HCC vary significantly from patient to …

Nanoparticles based on nanotechnology and biotechnology have emerged as efficient
carriers for various biopharmaceutical agents including proteins and genes. In particular …