[HTML][HTML] 汉滩病毒Gc 的细胞免疫反应性评估和验证
谢明阳, 孙报增, 马思婕, 杨端, 罗程, 王越越, 曹宇宸… - 2023 - aammt.tmmu.edu.cn
目的筛选, 鉴定并验证汉滩病毒包膜糖蛋白C 末端(Hantaan virus glycoprotein C-terminal,
HTNV Gc) 上免疫反应性表位. 方法在预测覆盖率超过全球98% 人群主要组织相容性复合物 …
HTNV Gc) 上免疫反应性表位. 方法在预测覆盖率超过全球98% 人群主要组织相容性复合物 …
[HTML][HTML] HLA preferences for conserved epitopes: a potential mechanism for hepatitis C clearance
X Rao, I Hoof, D Van Baarle, C Keşmir… - Frontiers in …, 2015 - frontiersin.org
Hepatitis C virus (HCV) infections affect more than 170 million people worldwide. Most of
these individuals are chronically infected, but some clear the infection rapidly. Host factors …
these individuals are chronically infected, but some clear the infection rapidly. Host factors …
Prioritizing candidate peptides for cancer vaccines through predicting peptide presentation by HLA-I proteins
LY Zhou, F Zou, W Sun - Biometrics, 2023 - academic.oup.com
Cancer (treatment) vaccines that are made of neoantigens, or peptides unique to tumor cells
due to somatic mutations, have emerged as a promising method to reinvigorate the immune …
due to somatic mutations, have emerged as a promising method to reinvigorate the immune …
[HTML][HTML] Comprehensive profiling of cancer neoantigens from aberrant RNA splicing
DP Wickland, C McNinch, E Jessen… - … for Immunotherapy of …, 2024 - ncbi.nlm.nih.gov
Background Cancer neoantigens arise from protein-altering somatic mutations in tumor and
rank among the most promising next-generation immuno-oncology agents when used in …
rank among the most promising next-generation immuno-oncology agents when used in …
An efficient hybrid deep learning architecture for predicting short antimicrobial peptides
Short‐length antimicrobial peptides (AMPs) have been demonstrated to have intensified
antimicrobial activities against a wide spectrum of microbes. Therefore, exploration of novel …
antimicrobial activities against a wide spectrum of microbes. Therefore, exploration of novel …
[HTML][HTML] Towards a gamete matching platform: using immunogenetics and artificial intelligence to predict recurrent miscarriage
A Mora-Sánchez, DI Aguilar-Salvador, I Nowak - NPJ digital medicine, 2019 - nature.com
The degree of Allele sharing of the Human Leukocyte Antigen (HLA) genes has been linked
with recurrent miscarriage (RM). However, no clear genetic markers of RM have yet been …
with recurrent miscarriage (RM). However, no clear genetic markers of RM have yet been …
T-cell epitope discovery for therapeutic cancer vaccines
S Krishna, KS Anderson - Vaccine Design: Methods and Protocols: Volume …, 2016 - Springer
The success of recent immune checkpoint blockade trials in solid tumors has demonstrated
the tremendous potential of immune-mediated treatment strategies for cancer therapy …
the tremendous potential of immune-mediated treatment strategies for cancer therapy …
[HTML][HTML] Designing of a multiepitope-based chimeric vaccine against dengue virus serotype 3 (DENV-3) through next generation reverse vaccinology approaches
The dengue virus (DENV) causes dengue infection and has become a significant global
public health concern. The successful application of immunotherapies in treating dengue …
public health concern. The successful application of immunotherapies in treating dengue …
Soluble HLA technology as a strategy to evaluate the impact of HLA mismatches
H Kunze-Schumacher, R Blasczyk… - Journal of …, 2014 - Wiley Online Library
HLA class I incompatibilities still remain one of the main barriers for unrelated bone marrow
transplantation (BMT); hence the molecular understanding of how to mismatch patients and …
transplantation (BMT); hence the molecular understanding of how to mismatch patients and …
Entropic analysis of antigen-specific CDR3 domains identifies essential binding motifs shared by CDR3s with different antigen specificities
Antigen-specific T cell receptor (TCR) sequences can have prognostic, predictive, and
therapeutic value, but decoding the specificity of TCR recognition remains challenging …
therapeutic value, but decoding the specificity of TCR recognition remains challenging …